Functional Recovery in Critically Ill Children, the Wee-Cover Multicentre Study

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

182 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-08-31

Study Completion Date

2016-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

When children suffer from a critical-illness, the investigators focus on resuscitating and saving lives. Once these children leave the pediatric intensive care unit, very little is known about what happens to them - how long it takes for them to recover, how families cope, and what factors that impede their recovery. The specific objective of this research project is to evaluate how children and their families recover after a critical illness.

Research Hypotheses: Following a critical illness in children, 1) the rate and degree of health and functional recovery is influenced by the following factors: age, pre-admission co-morbid status, critical illness severity, discharge functional status, and time to initiating acute rehabilitation; 2) functional recovery is influenced by caregiver burden and health-related quality-of-life (HRQoL).

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Identifying and Understanding Risk Factors for Instability and Adverse Events Associated With Chest Physiotherapy in Ventilated Children

NCT04146753

Respiratory Failure

COMPLETED

Nutrition Support During Pediatric Critical Illness - 2nd Multicenter, International Cohort Study

NCT02354521

Nutrition

COMPLETED

Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs

NCT02493478

Failed or Difficult Intubation, Sequela Intubation; Difficult Intubation Complication

RECRUITING

Oxy-PICU Neurodevelopmental Follow-up Study

NCT06734715

Intensive Care Pediatric

NOT_YET_RECRUITING

Transition From Paediatric Intensive Care to General Paediatrics and Pneumology Units : a Study of the Post-intensive Care Syndrome

NCT05587595

Pediatric Post-intensive Care Syndrome Intensive Care Unit Syndrome

UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The Specific Objective of this study is to evaluate the trajectory of health and functional outcomes in children following a critical illness, define poor functional recovery, and evaluate predictors of poor recovery.

The Research Questions for this study are: 1) What are the health and functional outcomes in children affected by a critical illness, at 3 and 6 months following Pediatric Intensive Care Unit (PICU) discharge? 2) What defines poor functional recovery? 3) What are predictors of poor functional recovery in critically ill children? 4) What are the most important and relevant outcomes in critically ill children, from the patient and caregiver's point of view?

Study Design: Prospective Observational Mixed Methods Longitudinal Cohort Study Study Setting: Two Academic Pediatric Centres in Canada - McMaster Children's Hospital and London Health Sciences Centre.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pediatric Critical Illness

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Critically ill children

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age over 12 months to 17 years
* Admitted to PICU for at least 48 hours
* ≥ one organ dysfunction on admission
* Informed consent of patient/substitute decision maker, and patient assent were appropriate

Exclusion Criteria

* Patients transferred directly from a neonatal intensive care unit prior to discharge home
* Patients who are already mobilizing well, or are at baseline functional status at time of screening
* Previous enrolment into this study
* Language barrier (i.e. no access to translation services)

Minimum Eligible Age

12 Months

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No