Laboratory Characteristics in Chronic Atrophic Acrodermatitis

NCT ID: NCT02147262

Last Updated: 2018-05-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-07-31

Study Completion Date

2020-07-31

Brief Summary

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The main objective of this study is to characterize the inflammatory proteins, gene polymorphisms, and transcriptome profiles in patients with chronic atrophic dermatitis to gain better insight into pathogenesis of chronic infection with Borrelia burgdorferi sensu lato.

Detailed Description

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Conditions

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Chronic Atrophic Acrodermatitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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ACA-doxy 14 days

patients with chronic atrophic acrodermatitis treated with doxycycline for 14 days

Group Type ACTIVE_COMPARATOR

doxycycline orally, 100 mg, bid, 14 days

Intervention Type DRUG

ACA-doxy 28 days

patients with chronic atrophic acrodermatitis treated with doxycycline for 28 days

Group Type ACTIVE_COMPARATOR

doxycycline orally, 100 mg, bid, 28 days

Intervention Type DRUG

Interventions

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doxycycline orally, 100 mg, bid, 14 days

Intervention Type DRUG

doxycycline orally, 100 mg, bid, 28 days

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* chronic atrophic dermatitis in patients \>18 years

Exclusion Criteria

* none
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Ljubljana School of Medicine, Slovenia

OTHER

Sponsor Role collaborator

Medical University of Vienna

OTHER

Sponsor Role collaborator

Harvard University

OTHER

Sponsor Role collaborator

University Medical Centre Ljubljana

OTHER

Sponsor Role lead

Responsible Party

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Franc Strle

M.D., PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Franc Strle, MD, PhD

Role: STUDY_CHAIR

UMC Ljubljana

Dasa Stupica, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

UMC Ljubljana

Locations

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UMC Ljubljana, Department of Infectious Diseases

Ljubljana, , Slovenia

Site Status RECRUITING

Countries

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Slovenia

Central Contacts

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Dasa Stupica, MD, PhD

Role: CONTACT

+386 1 522 2110

Franc Strle, MD, PhD

Role: CONTACT

+386 1 522 2610

Facility Contacts

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Dasa Stupica, MD,PhD

Role: primary

+386 1 522 2110

Franc Strle, MD,PhD

Role: backup

+386 1 522 2610

Other Identifiers

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ACA-0613

Identifier Type: -

Identifier Source: org_study_id

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