Safety and Efficacy of Overnight Closed Loop in Children With Type 1Diabetes Mellitus in Luxembourg

NCT ID: NCT02099409

Last Updated: 2014-09-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-01-31

Study Completion Date

2014-08-31

Brief Summary

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The purpose of this study is to validate current algorithms and evaluate safety and efficacy of overnight closed loop insulin delivery (FlorenceD2 system) in children with type 1 diabetes between 6 - 12 years of age in Luxembourg .

Detailed Description

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Conditions

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Type 1 Diabetes Mellitus

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Starting with FLORENCED2 followed by open loop

Start 2 Overnight periods with closed loop through FLORENCED2 Device , followed by 2 overnight periods with open loop.

Group Type EXPERIMENTAL

FLORENCED2

Intervention Type DEVICE

FLORENCED2 device ensures the closed loop between Freestyle Navigator II and the DANA DIABECARE R

Start open loop followed by FLORENCED2

Start with 2 overnight periods with open loop , followed by 2 overnight with closed loop FLORENCED2

Group Type EXPERIMENTAL

FLORENCED2

Intervention Type DEVICE

FLORENCED2 device ensures the closed loop between Freestyle Navigator II and the DANA DIABECARE R

Interventions

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FLORENCED2

FLORENCED2 device ensures the closed loop between Freestyle Navigator II and the DANA DIABECARE R

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Between 6 - ≤12 years
* With type 1 diabetes for 6 months or more and
* Pump user for at least 6 months.
* HbAc1 should be \<11 %.
* No medication or physical or psychological disease should be present, which could interfere with the study.

Exclusion Criteria

-None
Minimum Eligible Age

6 Years

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Cambridge

OTHER

Sponsor Role collaborator

Centre Hospitalier du Luxembourg

OTHER

Sponsor Role lead

Responsible Party

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Carine de Beaufort

MD , PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Carine deBeaufort, MD PhD

Role: PRINCIPAL_INVESTIGATOR

Centre Hospitalier du Luxembourg

Roman Hovorka, Professor

Role: PRINCIPAL_INVESTIGATOR

University of Cambridge

Gosia Wilinska, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Cambridge

Ulrike Schierloh, MD

Role: PRINCIPAL_INVESTIGATOR

Centre Hospitalier du Luxembourg

Locations

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DECCP Clinique Pédiatrique de Luxembourg/CHL

Luxembourg, , Luxembourg

Site Status

DECCP Pediatric Clinic , CHLuxembourg

Luxembourg, , Luxembourg

Site Status

Countries

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Luxembourg

Other Identifiers

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SPIDLUX 4

Identifier Type: -

Identifier Source: org_study_id

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