Inhalation Intervention for Nausea in the Emergency Department

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-04-30

Study Completion Date

2015-06-30

Brief Summary

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Randomized controlled trial comparing inhalation of isopropyl alcohol vs placebo (normal saline) pads to treat nausea in emergency department patients.

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Detailed Description

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This study is to investigate if inhaling the scent of a typical medical alcohol prep pad will alleviate nausea as compared to a identically packaged normal saline prep pad for the Emergency Department patient with nausea. The study length will be 10 minutes long. The subjects will take several deep nasal inhalations at the 0, 2, 5 minute marks. Level of nausea will be recorded during these times and at 10 minutes. The investigators will also assess satisfaction of the intervention. As in previous post operative unit studies,the hypothesis is that there will a significant difference in levels of nausea between the alcohol pad group versus the normal saline pad group.

Conditions

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Nausea Vomiting

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Alcohol prep pad group

isopropyl alcohol prep pad

Group Type ACTIVE_COMPARATOR

Alcohol prep pad group

Intervention Type OTHER

Subjects inhale scent of alcohol pad

Normal Saline prep pad

normal saline prep pad

Group Type PLACEBO_COMPARATOR

Normal Saline prep pad

Intervention Type OTHER

Subjects inhale scent of placebo (normal saline) pads

Interventions

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Alcohol prep pad group

Subjects inhale scent of alcohol pad

Intervention Type OTHER

Normal Saline prep pad

Subjects inhale scent of placebo (normal saline) pads

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* age range of 18-65 years of age
* complaint of nausea and or vomiting
* ability to breathe through nose
* ability to read and write English

Exclusion Criteria

* allergy to isopropyl alcohol
* pregnancy or pregnancy status unknown to subject. Pregnancy test only if part of clinical course.
* recent upper respiratory infection
* recent intake of cefoperazone, disulfiram, or metronidazole or any other medications that are known produce nausea when exposed to alcohol.
* use of antiemetic or psychoactive drug within 24 hours
* alcohol abuse
* nicotine within last 4 hrs

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No