Application of Combined Lumbar Plexus and Sciatic Nerve Block

NCT ID: NCT02084368

Last Updated: 2014-09-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-01-31

Study Completion Date

2014-02-28

Brief Summary

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The research is to study the effectiveness and safety of combined lumbar plexus and sciatic nerve block by the guide of peripheral nerve stimulator (PNS) in unilateral knee replacement.There have be some papers which supported that combined lumbar plexus and sciatic nerve block may be more suitable for the old men.

Detailed Description

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Conditions

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Anesthesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Nerve block

Patients in this group were assigned to receive lumbar plexus block and sciatic nerve block guided by PNS.

Group Type EXPERIMENTAL

Nerve block

Intervention Type PROCEDURE

Patients in this group were assigned to receive lumbar plexus block and sciatic nerve block both using 0.33% ropivacaine 30ml guided by PNS

Ropivacaine

Intervention Type DRUG

Patients will be assigned to receive lumbar plexus block and sciatic nerve block both using 0.33% ropivacain 30ml guided by PNS.

combined spinal and epidural anesthesia

Combined spinal and epidural anesthesia were performed in patients of this group.

Group Type PLACEBO_COMPARATOR

Combined spinal and epidural anesthesia

Intervention Type PROCEDURE

Combined spinal and epidural anesthesia were performed in patients of this group with 0.5% hyperbaric bupivacaine 8\~10mg at L2-3 or L3-4.

Bupivacaine

Intervention Type DRUG

Combined spinal and epidural anesthesia will be performed in patients with 0.5% hyperbaric bupivacaine 8\~10mg.

Interventions

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Nerve block

Patients in this group were assigned to receive lumbar plexus block and sciatic nerve block both using 0.33% ropivacaine 30ml guided by PNS

Intervention Type PROCEDURE

Combined spinal and epidural anesthesia

Combined spinal and epidural anesthesia were performed in patients of this group with 0.5% hyperbaric bupivacaine 8\~10mg at L2-3 or L3-4.

Intervention Type PROCEDURE

Ropivacaine

Patients will be assigned to receive lumbar plexus block and sciatic nerve block both using 0.33% ropivacain 30ml guided by PNS.

Intervention Type DRUG

Bupivacaine

Combined spinal and epidural anesthesia will be performed in patients with 0.5% hyperbaric bupivacaine 8\~10mg.

Intervention Type DRUG

Other Intervention Names

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0.33%Ropivacaine 0.5%Bupivacaine

Eligibility Criteria

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Inclusion Criteria

1. Patients of American Association of anesthetists(ASA)Grade 1、2 or 3
2. Aged between 18 and 85 years
3. Undergoing elective total knee replacement.

Exclusion Criteria

1. Mental illness can not match
2. Nerve block, epidural anesthesia contraindicated
3. People who have Slow-type arrhythmias
4. History of chronic headaches and long-term use of analgesic drugs
5. People who were postoperative consciousness, language or hearing impaired
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Guangzhou General Hospital of Guangzhou Military Command

OTHER

Sponsor Role lead

Responsible Party

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bo xu

associate chief physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Guangzhou Military Region General Hospital, Department of Anesthesiology

Guangzhou, Guangdong, China

Site Status

Countries

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China

References

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Farny J, Girard M, Drolet P. Posterior approach to the lumbar plexus combined with a sciatic nerve block using lidocaine. Can J Anaesth. 1994 Jun;41(6):486-91. doi: 10.1007/BF03011542.

Reference Type RESULT
PMID: 8069988 (View on PubMed)

de Leeuw MA, Slagt C, Hoeksema M, Zuurmond WW, Perez RS. Hemodynamic changes during a combined psoas compartment-sciatic nerve block for elective orthopedic surgery. Anesth Analg. 2011 Mar;112(3):719-24. doi: 10.1213/ANE.0b013e318206bc30. Epub 2010 Dec 14.

Reference Type RESULT
PMID: 21156977 (View on PubMed)

Other Identifiers

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Nerve Block

Identifier Type: -

Identifier Source: org_study_id

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