CVP-guided Aquapheresis for the Treatment of Acute Congestion in Heart Failure
NCT ID: NCT02079259
Last Updated: 2015-03-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
9 participants
OBSERVATIONAL
2013-11-30
2014-03-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
There is increasing evidence that ultrafiltration may relief cardiac congestion with lesser effects on blood pressure and activation of renin angiotensin system, respectively . However, recent studies revealed conflicting results: demonstration the superiority of ultrafiltration in comparison to diuretic treatment, and a lack of evidence of benefit, as well as an excess of adverse events with ultrafiltration.
Aquapheresis with adapted ultrafiltration rate guided by central venous pressure is safer than aquaphesis with a constant ultrafiltration with comparable effectiveness
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Ultrafiltration Versus Intravenous (IV) Diuretics for Patients Hospitalized for Acute Decompensated Heart Failure: (UNLOAD)
NCT00124137
Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation
NCT05909150
The Effect of Fluid Restriction in Congestive Heart Failure Complicated With Hyponatremia
NCT01748331
Optimization of Fluid Balance Guided by Bioelectrical Impedance Analysis in Patients Undergoing Continuous Renal Replacement Therapy in Critical Care
NCT06799910
Impact of Fluid Resuscitation on Venous Congestion in Cardiac Critically-ill Patients
NCT07183397
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
CASE_ONLY
PROSPECTIVE
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Ultrafiltration
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Indication for CVVH/Aquapheresis
Exclusion Criteria
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Heinrich-Heine University, Duesseldorf
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Klinik für Kardiologie, Pneumologie und Angiologie
Klinik für Kardiologie, Pneumologie und Angiologie
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Ralf Westenfeld, MD
Role: PRINCIPAL_INVESTIGATOR
Division of Cardiology, Pulmonary Diseases, Vascular Medicine, University Hospital Dusseldorf
Malte Kelm, MD
Role: STUDY_CHAIR
Division of Cardiology, Pulmonary Diseases, Vascular Medicine, University Hospital Dusseldorf
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Division of Cardiology, Pulmonary Diseases, Vascular Medicine, University Hospital Dusseldorf
Düsseldorf, , Germany
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
Aquadex
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.