Non-invasive Evaluation of Volume Status Using Exhaled Carbon Dioxide and Pulse Contour Analysis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

33 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-04-30

Study Completion Date

2015-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The investigators hypothesize that changes in blood circulation can be reflected by exhaled CO2 provided CO2-production in the tissues and ventilation from the lungs are stable. The investigators want to explore changes in cardiac output (the amount of blood being pumped out of the heart each minute) in patients using different devices: an esophagus ultrasound device measuring cardiac output, a finger cuff measuring blood pressure and cardiac output, and exhaled carbondioxide in the patients' breath measured by the ventilator.

The investigators investigate patients after bypass surgery or heart valve replacement, and induce changes in cardiac output with passive leg raise or ventricular pacing.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Pulse Contour Analysis and Tissue Oxymetry in Changing Vascular Tone

NCT00583687

Cardiac Output, High Cardiac Output, Low Vasodilation +2 more

COMPLETED NA

Agreement of the Nexfin™ Monitor With Non-invasive Blood Pressure Measurement

NCT02447471

Blood Pressure Measurement

COMPLETED

The Precision of Pulmonary Artery Cardiac Output-measurements in Spontaneously Breathing Patients

NCT01944254

Heart Diseases

COMPLETED NA

The Feasibility and Accuracy of Exhaled CO2 to Measure Cardiac Output in Ventilated Patients Without Tracheal Intubation

NCT00783679

Cardiac Physiology Cardiac Output

WITHDRAWN NA

Verification of Pulse Oximetry in Neonatal Population

NCT00751439

Respiratory Distress Syndrome

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Measurements with the finger cuff (pulse contour analyses) were aborted due to technical difficulties.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Changes in Cardiac Output

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Comparing cardiac output changes

Explore the relationship between changes in cardiac output measured with eosophagal Doppler, the volume-clamp-method and exhaled CO2 during ventricular pacing and passive leg raise.

Measurements with the volume-clamp-method were aborted due to technological difficulties.

Group Type EXPERIMENTAL