Evaluation of the Effects of Eccentric Muscle Training Versus Conventional Concentric Training in Chronic Heart Failure
NCT ID: NCT02046707
Last Updated: 2019-05-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
71 participants
INTERVENTIONAL
2014-08-29
Brief Summary
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In addition, a group of healthy volunteers aged between 20 and 85 years will also be recruited. This group will make it possible to evaluate, during the two exercise sessions, mechanisms of adaptation linked to eccentric exercise vs concentric exercise.
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
NONE
Study Groups
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Patients with chronic heart failure
initial evaluation
Period of cardiac rehabilitation
final evaluation
Controls
Concentric and eccentric exercise sessions
Interventions
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initial evaluation
Period of cardiac rehabilitation
final evaluation
Concentric and eccentric exercise sessions
Eligibility Criteria
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Inclusion Criteria
* Patients who have provided written informed consent
* Patients with national health insurance cover
* Men or women aged between 45 and 85 years with stabilized chronic heart failure (ischemic or dilated cardiopathy) for at least one month, New York Heart Association stage\> 2.
* Echocardiographic left ventricular ejection fraction (Simpson method) \< 45% OR N-terminal-ProBNP \> 3 x upper limit of normal\* (\*= 125pg/ml for the CHU laboratory).
* First period of rehabilitation for chronic heart failure.
Healthy volunteers:
* Subjects who have provided written informed consent
* Subjects with national health insurance cover
* Men or women aged between 18 and 85 years.
Healthy volunteers:
* persons without national health insurance cover
* Any organic disorder whatever its nature (cardiac, respiratory, neurological, orthopedic, …) that could affect adaptation to effort or is a contra-indication for physical activity.
Exclusion Criteria
* persons without national health insurance cover
* Severe obstructive cardiopathy,
* severe aortic valve stenosis,
* severe progressive heart rhythm or conduction disorders not corrected with a pacemaker, discovered at the initial effort test
* intra-cavitary thrombus,
* severe pulmonary artery hypertension (systolic pulmonary arterial hypertension \>70mmHg),
* recent history of venous trombo-embolism (last 3 months),
* impaired executive function making it impossible to understand and follow reconditioning programme (Mini Mental Test \< 24),
* heart transplant,
* associated medical disorders that could predominately impair functional capacity compared with the chronic heart failure (examples: respiratory insufficiency, non-stabilized metabolic disorders such as progressive kidney failure, severe asthenia related to a severe non-stabilized disorder such as neoplasia, systemic disease…).
45 Years
85 Years
ALL
No
Sponsors
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Centre Hospitalier Universitaire Dijon
OTHER
Responsible Party
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Locations
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CHU de Dijon
Dijon, , France
Countries
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Other Identifiers
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CASILLAS Fondation Av 2008
Identifier Type: -
Identifier Source: org_study_id
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