Effect of Dexmedetomidine on Bispectral Index and Propofol Requirements During Different Menstrual Cycle

NCT ID: NCT02035930

Last Updated: 2014-01-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

110 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-11-30

Study Completion Date

2012-11-30

Brief Summary

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The study was done to evaluate the effects of the follicular and luteal phases of the menstrual cycle on sedation level at loss of consciousness and bispectral index reach to 50 during propofol anesthesia, in patients with and without preoperative intravenous dexmedetomidine .

Detailed Description

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Conditions

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Abnormal Menstrual Cycle

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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menstrual cycle,dexmedetomidine

Group Type OTHER

dexmedetomidine

Intervention Type DRUG

Interventions

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dexmedetomidine

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* a regular menstrual cycle
* elective gynecologic surgery

Exclusion Criteria

* pregnancy
* breastfeeding
* obesity
* known hypersensitivity to drugs used in the study protocol;
* use of psychotropic drugs and steroids within 72 hours before the surgery
* central nervous system injury
* renal impairment
* alcoholism and opioid addiction.
Minimum Eligible Age

24 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Fudan University

OTHER

Sponsor Role lead

Responsible Party

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Geng guiqi

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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TWang

Identifier Type: -

Identifier Source: org_study_id

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