The Feasibility of PetCO2 Prediction Hypotension Under Spinal Anesthesia for Cesarean Section

NCT ID: NCT02032355

Last Updated: 2014-01-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

6 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-31

Study Completion Date

2014-02-28

Brief Summary

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Maternal hypotension is a common side effect after spinal anesthesia for cesarean delivery.Decreased vascular resistance and cardiac output, due to sympathetic blockade1and blood pooling in blocked areas of the body respectively, are main causes of spinal anaesthesia-induced hypotension during Caesarean delivery.

Cardiac output, which has shown to be a better predictor of organ and placental perfusion than arterial blood pressure.Few studies have measured CO after spinal anesthesia in the maternal population.This is largely because of the lack of availability of accurate and reproducible noninvasive measurement techniques. Up to now, preventing hypotension has continued to focus on arterial blood pressure variables, fluid, and ephedrine requirements as markers of cardiovascular status, because these are more easily measured.

Investgators hypothesized that CO and PetCO2, in parturients with the degree of hypotension during spinal anaesthesia, would also have a positive and significant association.

Detailed Description

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Conditions

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Hypotension Carbon Dioxide

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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hypotension

spinal anesthesia

Intervention Type PROCEDURE

Interventions

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spinal anesthesia

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* full-term gestation (\>36 and \<41 weeks of gestation) with a singleton pregnancy

Exclusion Criteria

* emergency cases
* placenta praevia
* preeclampsia
* cardiovascular or cerebrovascular disease
* morbid obesity with a BMI≥40
* contraindications to spinal anaesthesia
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Geng guiqi

OTHER

Sponsor Role lead

Responsible Party

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Geng guiqi

professor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Obstetrics & Gynecology Hospital, Fudan University

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

Countries

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China

Facility Contacts

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congjian xu, PhD

Role: primary

86 2163455050

Other Identifiers

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61538

Identifier Type: -

Identifier Source: org_study_id

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