Study of Magnetic Brain Stimulation in Treatment of Obsessive Compulsive Disorder
NCT ID: NCT02018185
Last Updated: 2021-03-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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SUSPENDED
NA
30 participants
INTERVENTIONAL
2014-01-31
2021-08-31
Brief Summary
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In the current proposal, in a randomized clinical trial, the investigators aim to further evaluate the efficacy of rTMS in OCD in a larger sample size and for a longer period. Studies into the efficacy of rTMS in other psychiatric disorders such as depression have consistently shown that extension of the treatment to four weeks significantly increased the effect size. In the pilot study, the investigators applied rTMS for only two weeks. Although all patients consistently showed improvement in their symptoms, none of them showed complete remission of their OCD. Here, the investigators hypothesize that longer duration of rTMS treatment will have greater benefit in OCD symptom reduction.
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Detailed Description
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rTMS will be provided to OCD patients in a randomized double blind controlled setting, and the investigators hypothesize that in this setting the treatment group would still show significant improvement in OCD symptoms as compared to the sham group.
rTMS will be applied for four weeks on OCD patients and the investigators will assess improvement after four weeks of rTMS. The investigators hypothesize that patients will show significantly greater improvement after four weeks of rTMS vs. two weeks of rTMS.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Transcranial Magnetic Stimulation
Transcranial Magnetic Stimulation
Transcranial Magnetic Stimulation
A non-invasive method for brain stimulation
Sham rTMS
Sham Transcranial Magnetic Stimulation
Sham Transcranial Magnetic Stimulation
Sham stimulation of the brain.
Interventions
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Transcranial Magnetic Stimulation
A non-invasive method for brain stimulation
Sham Transcranial Magnetic Stimulation
Sham stimulation of the brain.
Eligibility Criteria
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Inclusion Criteria
* Not currently receiving cognitive behavioural therapy
* Not currently on any medication or only taking one selective serotonin reuptake inhibitor (SSRI)
Exclusion Criteria
* History of neurological illness
* Previous head injury
* Active alcohol or substance abuse
* History of seizure disorders
* Currently pregnant
18 Years
80 Years
ALL
No
Sponsors
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Manitoba Medical Service Foundation
OTHER
University of Manitoba
OTHER
Responsible Party
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Locations
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St. Boniface Hospital
Winnipeg, Manitoba, Canada
Countries
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Other Identifiers
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B2013:144
Identifier Type: -
Identifier Source: org_study_id
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