The Effect of Systemic Lidocaine Infusion to Postoperative Pain and Quality of Recovery After Laparoscopic Hernia Repair in Children

NCT ID: NCT02007330

Last Updated: 2015-06-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

66 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-11-30

Study Completion Date

2015-01-31

Brief Summary

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Systemic lidocaine administration may improve postoperative pain and recovery after laparoscopic inguinal hernia repair in pediatric patients

Detailed Description

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Conditions

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Inguinal Hernia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Group L

Intravenous lidocaine infusion group

Group Type EXPERIMENTAL

Systemic intravenous lidocaine infusion

Intervention Type DRUG

In group L, intravenous lidocaine infusion (0.1mg/kg) for 1minutes after induction of anesthesia. After 1 minutes, lidocaine infusion continued at rate of 1.5mg/kg/hr during operation, and discontinued before move the patients to PACU.

Group C

Intravenous normal saline infusion - control group

Group Type PLACEBO_COMPARATOR

Normal saline infusion

Intervention Type DRUG

In group C, the patients receive same volume of normal saline

Interventions

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Systemic intravenous lidocaine infusion

In group L, intravenous lidocaine infusion (0.1mg/kg) for 1minutes after induction of anesthesia. After 1 minutes, lidocaine infusion continued at rate of 1.5mg/kg/hr during operation, and discontinued before move the patients to PACU.

Intervention Type DRUG

Normal saline infusion

In group C, the patients receive same volume of normal saline

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Age between 1 and 6 year-old
* ASA class 1 and 2
* Pediatric Inguinal hernia patients who are scheduled for elective laparoscopic inguinal hernia repair

Exclusion Criteria

* Allergy to local anesthetics or contraindication to use of lidocaine
* Current active upper respiratory infection or history of upper respiratory infection within 2 weeks
* Severe cardiovascular disease
* Renal failure
* Liver failure
* Neurologic and psychologic disease
* Chronic treatment with analgesics
* Previous history of laparoscopic operation
* Parents' refusal
Minimum Eligible Age

1 Year

Maximum Eligible Age

6 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yonsei University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei Universiy College of Medicine

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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4-2013-0692

Identifier Type: -

Identifier Source: org_study_id

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