Historical Data Analysis of Hematological Remission and Survival in Adults With R/R Acute Lymphoblastic Leukemia
NCT ID: NCT02003612
Last Updated: 2022-11-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
2373 participants
OBSERVATIONAL
2013-10-01
2014-04-28
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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All subjects
All subjects
Not applicable - observational study
No intervention exists as this is a retrospective observational study
Interventions
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Not applicable - observational study
No intervention exists as this is a retrospective observational study
Eligibility Criteria
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Inclusion Criteria
* age 15 or older at time of de novo (initial) diagnosis of acute lymphoblastic leukemia
* initial diagnosis of acute lymphoblastic leukemia in the year 1990 or later
* No CNS involvement at relapse
* No isolated extramedullary relapse
15 Years
ALL
No
Sponsors
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Amgen
INDUSTRY
Responsible Party
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Principal Investigators
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MD
Role: STUDY_DIRECTOR
Amgen
Locations
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Research Site
Boston, Massachusetts, United States
Research Site
Cleveland, Ohio, United States
Research Site
Brno, , Czechia
Research Site
Paris, , France
Research Site
Frankfurt am Main, , Germany
Research Site
Bologna, , Italy
Research Site
Venezia, , Italy
Research Site
Gliwice, , Poland
Research Site
Badalona, Catalonia, Spain
Research Site
London, , United Kingdom
Countries
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References
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Barlev A, Lin VW, Katz A, Hu K, Cong Z, Barber B. Estimating Long-Term Survival of Adults with Philadelphia Chromosome-Negative Relapsed/Refractory B-Precursor Acute Lymphoblastic Leukemia Treated with Blinatumomab Using Historical Data. Adv Ther. 2017 Jan;34(1):148-155. doi: 10.1007/s12325-016-0447-x. Epub 2016 Nov 21.
Gokbuget N, Dombret H, Ribera JM, Fielding AK, Advani A, Bassan R, Chia V, Doubek M, Giebel S, Hoelzer D, Ifrah N, Katz A, Kelsh M, Martinelli G, Morgades M, O'Brien S, Rowe JM, Stieglmaier J, Wadleigh M, Kantarjian H. International reference analysis of outcomes in adults with B-precursor Ph-negative relapsed/refractory acute lymphoblastic leukemia. Haematologica. 2016 Dec;101(12):1524-1533. doi: 10.3324/haematol.2016.144311. Epub 2016 Sep 1.
Related Links
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AmgenTrials clinical trials website
Other Identifiers
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20120310
Identifier Type: -
Identifier Source: org_study_id
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