Jugular Venous Flow Healthy Volunteers

NCT ID: NCT02002494

Last Updated: 2020-06-04

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 27 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2013-06-30
• Study Completion Date: 2014-02-28

Brief Summary

Our hypothesis is that there will be a decrease in internal jugular venous flow in the park bench position when compared to the supine position. There will also be a change in blood flow in the between right and left internal jugular veins in park bench position, particularly there will be a greater reduction of flow on the dependent side. However, the internal jugular venous flow will be the same in both the prone and supine position.

Detailed Description

The different positions used in neurosurgery (park bench, prone) for better accessibility to the operating field can impact on the cerebral venous drainage due to the effects of internal jugular venous outflow of blood and may increase intracranial pressure. The kinking of the internal jugular vein due to excessive neck flexion and rotation in park bench or flexion in the prone position may lead to kinking or twisting of the vein. This has been hypothesized as the major cause of disturbed venous drainage during surgery and in postoperative patients may lead to neck swelling, brachial plexus injury, macroglossia (swollen tongue), delayed airway obstruction and increases in intracranial pressure.

Optimal brain perfusion is best in the neutral position of the head, but surgery cannot always be performed with this. Thus, we look to measure the internal jugular venous flow at different positions as there have been little studies looking at this important contributing factor.

Conditions

Jugular Venous Blood Flow

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

volunteers in different positions

The following will be compared in the same volunteer:

• Bilateral internal jugular venous flow in supine and prone position
• Bilateral internal jugular venous flow in supine and park bench position
• Bilateral internal jugular venous flow in prone and park bench

Different positions

Intervention Type: OTHER

Jugular venous blood flow in healthy volunteers in 3 different positions- supine, prone and park bench

Interventions

Different positions

Jugular venous blood flow in healthy volunteers in 3 different positions- supine, prone and park bench

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Adult healthy volunteers who are above the age of 18
• American Society of Anesthesiologists classification (ASA) 1
• Body mass index (BMI) less than and equal to 35

Exclusion Criteria

• ASA 2 and above
• BMI above 35
• Lack of informed consent
• Language barrier
• Medical students and anaesthesia residents going through the department as part of their rotation

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University Health Network, Toronto

OTHER

Sponsor Role: lead

Responsible Party

Lashmi Venkatraghavan

Dr.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Lashmi Venkatraghavan

Role: PRINCIPAL_INVESTIGATOR

University Health Network, Toronto Western Hospital

Vincent Chan

Role: PRINCIPAL_INVESTIGATOR

University Health Network, Toronto Western Hospital

Pirjo Manninen

Role: PRINCIPAL_INVESTIGATOR

University Health Network, Toronto Western Hospital

Audrey MY Tan

Role: PRINCIPAL_INVESTIGATOR

University Health Network, Toronto Western Hospital

Locations

University Health Network, Toronto Western Hospital

Toronto, Ontario, Canada

Countries

Canada

Other Identifiers

13-6244-BE

Identifier Type: -

Identifier Source: org_study_id