Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
TERMINATED
NA
30 participants
INTERVENTIONAL
2014-01-31
2019-01-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
This study aims to test whether the use of a nicotine patch may accelerate the healing process from AVN of the knee.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Steam Ablation Versus Endovenous Laser Ablation for the Treatment of Great Saphenous Veins
NCT02046967
Effect of Nitroglycerin Ointment on Mastectomy Flap Necrosis
NCT01608880
Clinical Evaluation of Hemospray in Hemostasis of Active Variceal Bleeding
NCT01783899
Nitrous Oxide Vasodilation Healthy Adult Volunteers
NCT01785030
Compression Aided Management of Edema in Patients With C3 Venous Disease
NCT00766974
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
This is a double-blind prospective study that will include 50 adult volunteers, randomly assigned to a "nitrate" group that will be given a nitrate patch, and a "placebo" group that will be given a placebo patch.
The following outcomes will be measured:
* MRI findings before and after the patch treatment
* Use of analgesics
* Subjective pain relief.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
study group
the patients that will get a nitrate patch
nitrate patch
patients in the study group will get a nitrate patch
MRI scan
MRI scan after 6 weeks of treatment
control group
the patients that will get the placebo patch
placebo patch
control group patients will get a placebo patch
MRI scan
MRI scan after 6 weeks of treatment
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
nitrate patch
patients in the study group will get a nitrate patch
placebo patch
control group patients will get a placebo patch
MRI scan
MRI scan after 6 weeks of treatment
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* diagnosis of AVN according to MRI
Exclusion Criteria
* Cognitive impairment / any condition disturbing informed concent.
* Nitrate intolerance
* Patients using Cyclic GMP inhibitiors
18 Years
80 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Sheba Medical Center
OTHER_GOV
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Prof.Avi Livneh
head of internal medicine ward F
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
avi livneh
Role: PRINCIPAL_INVESTIGATOR
Sheba Medical Center
arik asman, MD
Role: STUDY_DIRECTOR
Sheba Medical Center
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Sheba Medical Center
Ramat Gan, , Israel
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
SHEBA-12-9707-AL-CTIL
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.