The Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN)

NCT ID: NCT01973829

Last Updated: 2018-08-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

5215 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-11-30

Study Completion Date

2018-03-31

Brief Summary

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The purpose of the study is to test whether the health care provider access and training in CERTAIN (Checklist for Early Recognition and Treatment of Acute Illness), would facilitate timely and error free best-practice delivery and minimize preventable death and costly complications in critically ill patients.

Detailed Description

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Conditions

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Critical Illness Sepsis Respiratory Failure Shock Coma Bleeding Trauma

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Baseline arm

baseline data (50 patients or 3 months per center)

Group Type OTHER

Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN)

Intervention Type OTHER

This study is about training and implementation of best critical care practices in the international ICUs with variable resources facilitated by access to a specifically designed electronic checklist

Interventions

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Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN)

This study is about training and implementation of best critical care practices in the international ICUs with variable resources facilitated by access to a specifically designed electronic checklist

Intervention Type OTHER

Other Intervention Names

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Checklist

Eligibility Criteria

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Inclusion Criteria

All adult (≥ 18 years) patients admitted for the first time to the participating ICUs will be included.

Exclusion:

Not critically Ill, admitted for low risk monitoring, planned ICU admissions for routine postoperative surveillance for less than 24 hours after uncomplicated surgery, readmission and transferred from outside ICU.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Ognjen Gajic

CONS-CRITICAL CARE

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ognjen Gajic, MD

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Marija Kojicic, MD

Role: PRINCIPAL_INVESTIGATOR

Institute for Pulmonary Diseases, Novi Sad, Serbia

Rahul Kashyap, MD

Role: STUDY_DIRECTOR

Mayo Clinic

Marcus Schultz, MD

Role: PRINCIPAL_INVESTIGATOR

University of Amsterdam

Michelle N Gong, MD

Role: PRINCIPAL_INVESTIGATOR

Montefiore Medical Center, New York USA

Oguz Kilickaya, MD

Role: PRINCIPAL_INVESTIGATOR

Gulhane Military Medical Faculty, Ankara, Turkey

Neill Adhikari, MD

Role: PRINCIPAL_INVESTIGATOR

University of Toronto, Toronto Canada

Linda Bucher, PhD

Role: PRINCIPAL_INVESTIGATOR

College of Health Sciences, University of Delavere, Delawere USA

Daniel Talmor, MD

Role: PRINCIPAL_INVESTIGATOR

Beth Israel Deakoness Medical Center, Boston USA

Yue Dong, MD

Role: STUDY_DIRECTOR

Mayo Clinic

Locations

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Gomel Regional Clinical Hospital

Homyel, , Belarus

Site Status

University Hospital Banja Luka

Banja Luka, , Bosnia and Herzegovina

Site Status

Sveučilišna klinička bolnica

Mostar, , Bosnia and Herzegovina

Site Status

Prim.Dr. Abdulah Nakaš

Sarajevo, , Bosnia and Herzegovina

Site Status

Hospital Israelita Albert Einstein

São Paulo, , Brazil

Site Status

Beijing Hospital

Beijing, , China

Site Status

Guang An Men Hospital

Beijing, , China

Site Status

China West China Hospital

Chengdu, , China

Site Status

1st Affiliated Hospital of Guangzhou Medical University

Guangzhusi, , China

Site Status

Anhui Province Hospital

Hefei, , China

Site Status

China Shanghai Changhai Hospital

Shanghai, , China

Site Status

Tianjin First Center Hospital

Tianjin, , China

Site Status

KBC Rijeka

Rijeka, , Croatia

Site Status

Centro De Diagnostica Imagenes Medicina Avanzada y Telemedicina CEDIMAT

Santo Domingo, , Dominican Republic

Site Status

Kasturba Hospital

Manial, Karnataka, India

Site Status

Lok Nayak Hospital

New Delhi, National Capital Territory of Delhi, India

Site Status

Ispat General Hospital

Raurkela, Odisha, India

Site Status

St James Hosptial

Dublin, , Ireland

Site Status

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMNSZ)

Mexico City, , Mexico

Site Status

Central State University Hospital

Ulaanbaatar, , Mongolia

Site Status

Shaukat Khanum Memorial Cancer Hospital and Research Center

Lahore, , Pakistan

Site Status

St. Luke's Medical Center

Manila, , Philippines

Site Status

The Med City Hospital

Manila, , Philippines

Site Status

Heliodor Swiecicki Clinical Hospital at the Karol Marcinkowski Medical University in Poznań

Poznan, , Poland

Site Status

King Abdulaziz Medical City,

Riyadh, , Saudi Arabia

Site Status

Military Medical Academy

Belgrade, , Serbia

Site Status

The Institute for pulmonary diseases of Vojvodina

Kamenitz, , Serbia

Site Status

Akdeniz University Hospital

Antalya, , Turkey (Türkiye)

Site Status

Gulhane Military Medical Faculty

Antalya, , Turkey (Türkiye)

Site Status

International hospital Kampala

Kampala, , Uganda

Site Status

Countries

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Belarus Bosnia and Herzegovina Brazil China Croatia Dominican Republic India Ireland Mexico Mongolia Pakistan Philippines Poland Saudi Arabia Serbia Turkey (Türkiye) Uganda

References

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Vukoja M, Dong Y, Adhikari NKJ, Schultz MJ, Arabi YM, Martin-Loeches I, Hache M, Gavrilovic S, Kashyap R, Gajic O; Checklist for Early Recognition and Treatment of Acute Illness and Injury (CERTAIN) Investigators of the SCCM Discovery Network. Checklist for Early Recognition and Treatment of Acute Illness and Injury: An Exploratory Multicenter International Quality-Improvement Study in the ICUs With Variable Resources. Crit Care Med. 2021 Jun 1;49(6):e598-e612. doi: 10.1097/CCM.0000000000004937.

Reference Type DERIVED
PMID: 33729718 (View on PubMed)

Related Links

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http://icertain.org/

education and introduction website

Other Identifiers

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12-007998

Identifier Type: -

Identifier Source: org_study_id

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