Identification of Mechanism in the Erythroid Response in Patients With Myelodysplasia Undergoing Chelation Therapy

NCT ID: NCT01956799

Last Updated: 2023-02-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-05-31

Study Completion Date

2019-12-31

Brief Summary

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The study aims to evaluate the molecular mechanism underlying the erythroid response observed in some patients with myelodysplasia, myelofibrosis and aplastic anemia treated with Deferasirox or Deferoxamina.

Detailed Description

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Conditions

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Myelodysplasia Myelofibrosis Aplastic Anemia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. Patients aged 18 and older
2. Diagnosis of Myelodysplasia, myelofibrosis or aplastic anemia
3. transfusion-dependent anemia undergoing chelation therapy with deferasirox or deferoxamine

Exclusion Criteria

* none
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fondazione Italiana Sindromi Mielodisplastiche-ETS

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Daniela Cilloni, MD

Role: PRINCIPAL_INVESTIGATOR

AOU S. Luigi Gonzaga, Regione Gonzole 10, 10043 Orbassano (TO)

Locations

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Ematologia, AO SS. Antonio e Biagio

Alessandria, AL, Italy

Site Status

Clinica di Ematologia, AOU Ospedale di Torrette

Ancona, AN, Italy

Site Status

Ematologia con trapianto, AOU Policlinico di Bari

Bari, BA, Italy

Site Status

Istituto di Ematologia e Oncologia Medica, Policlinico S.Orsola

Bologna, BO, Italy

Site Status

Ematologia, Spedali Civili

Brescia, BS, Italy

Site Status

Struttura complessa di Ematologia, ASO S.Croce e Carle

Cuneo, CN, Italy

Site Status

Cattedra di Ematologia Policlino Careggi

Florence, FI, Italy

Site Status

Clinica Ematologica, Università di Genova

Genova, GE, Italy

Site Status

U.O. Clinica Medicina Interna, IRCCS San Martino IST

Genova, GE, Italy

Site Status

UO Ematologia e CTMO, Ospedale Civile G. da Saliceto

Piacenza, PC, Italy

Site Status

Ematologia, Università di Padova

Padua, PD, Italy

Site Status

Struttura Cattedra di Ematologia e CTMO, AOU di Parma

Parma, PR, Italy

Site Status

Ematologia e Centro Trapianti, Centro di Riferimento Oncologico della Basilicata

Rionero in Vulture, PZ, Italy

Site Status

Medicina Interna II Divisione di Ematologia, Ospedale S. Luigi Gonzaga

Orbassano, TO, Italy

Site Status

Ematologia 2, AOU Città della Salute e della Scienza

Torino, TO, Italy

Site Status

S.C.D.U. Ematologia e Terapie cellulari, Ospedale Mauriziano

Torino, TO, Italy

Site Status

UOC Ematologia, Ospedale S.Eugenio

Roma, , Italy

Site Status

Policlinico A.Gemelli

Roma, , Italy

Site Status

UOC Ematologia, AO S. Giovanni Addolorata

Roma, , Italy

Site Status

Ematologia, AO S. Andrea

Roma, , Italy

Site Status

Countries

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Italy

Other Identifiers

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FISM-BIOFER12

Identifier Type: -

Identifier Source: org_study_id

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