Effectiveness and Safety of New Botanical Component-LFCO- Compared With Existing TTO in Clinical Study
NCT ID: NCT01930565
Last Updated: 2013-08-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
34 participants
INTERVENTIONAL
2013-01-31
2013-07-31
Brief Summary
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Basically, this is a split face study - one side of face randomly assigned was applied with LFCO and the other side with TTO in same patients.
Detailed Description
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To compare the clinical efficacy, safety and histopathological changes between Lactobacillus fermented Chamaecypris obtusa (LFCO) and existing tea tree oil (TTO)
Total thirty four patients were instructed to apply 5 % LFCO to the involved areas of randomly allocated side and 5 % TTO extract to the other side for 8 weeks in a double blind split-face clinical trial.
Conditions
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Keywords
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Study Design
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RANDOMIZED
SINGLE_GROUP
TREATMENT
TRIPLE
Study Groups
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LFCO application
We made LFCO application(Lactobacillus Fermented Chamaecypris obtusa) containing cream to one side of patients' face to monitor effectiveness and safety in acne treatment.
LFCO application
Application of LFCO (Lactobacillus fermented Chamaecypris obtusa ) containing creams to one randomly selected face of patients to monitor its effectiveness and safety of acne treatments.
TTO application
To compare effectiveness and safety of new LFCO, we applied existing TTO containing cream to the other side of face in the same patients
TTO application
Application of TTO (Tea tree oil) containing creams to the other side of face of patients to monitor its effectiveness and safe compared with LFCO.
Interventions
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LFCO application
Application of LFCO (Lactobacillus fermented Chamaecypris obtusa ) containing creams to one randomly selected face of patients to monitor its effectiveness and safety of acne treatments.
TTO application
Application of TTO (Tea tree oil) containing creams to the other side of face of patients to monitor its effectiveness and safe compared with LFCO.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* active acne lesions in both sides of face
* available during study periods
Exclusion Criteria
19 Years
45 Years
ALL
Yes
Sponsors
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Seoul National University Hospital
OTHER
Responsible Party
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Dae Hun Suh
Professor
Principal Investigators
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Dae Hun Sun, MD
Role: STUDY_CHAIR
Seoul National University Hospital
Locations
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Department of Dermatology, Seoul National University College of Medicine
Seoul, , South Korea
Countries
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References
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Hayashi N, Kawashima M. Multicenter randomized controlled trial on combination therapy with 0.1% adapalene gel and oral antibiotics for acne vulgaris: comparison of the efficacy of adapalene gel alone and in combination with oral faropenem. J Dermatol. 2012 Jun;39(6):511-5. doi: 10.1111/j.1346-8138.2011.01450.x. Epub 2011 Dec 14.
Enshaieh S, Jooya A, Siadat AH, Iraji F. The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study. Indian J Dermatol Venereol Leprol. 2007 Jan-Feb;73(1):22-5. doi: 10.4103/0378-6323.30646.
Related Links
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Other Identifiers
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H-1209-069-427
Identifier Type: -
Identifier Source: org_study_id