"A Comparative Clinical Evaluation of the Efficacy of Topical Adapalene, Benzoyl Peroxide Gel, Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule, and Their Fixed Combination in Mild to Moderate Acne Vulgaris Patients."

NCT ID: NCT05855629

Last Updated: 2023-05-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

59 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-02-18

Study Completion Date

2023-07-30

Brief Summary

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The study aims to conduct a comparative clinical evaluation of the effectiveness of a fixed topical combination of adapalene with benzoyl peroxide in the form of a gel, a fixed combination of Lactobacillus rhamnosus, D-chiro-inositol and inulin in the form of capsules and their combination in patients with acne vulgaris of mild and moderate severity and laboratory lipid analysis profile of sebum, lipid metabolism, and IGF-1 (insulin-like growth factor).

Detailed Description

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Conditions

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Acne Vulgaris

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Topical Adapalene, Benzoyl Peroxide Gel

Group Type OTHER

Topical Adapalene, Benzoyl Peroxide Gel

Intervention Type DRUG

Adapalene 1mg/g, Benzoyl Peroxide 25mg/ml

Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule

Group Type OTHER

Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule

Intervention Type DIETARY_SUPPLEMENT

Lactobacillus Rhamnosus 1,5 х 10\*9, Inulin 25mg, D-chiro-inositol 250mg

Topical Adapalene,Benzoyl Peroxide Gel,Oral Lactobacillus Rhamnosus,D-chiro-inositol,Inulin Capsule

Group Type OTHER

Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule

Intervention Type DIETARY_SUPPLEMENT

Lactobacillus Rhamnosus 1,5 х 10\*9, Inulin 25mg, D-chiro-inositol 250mg

Topical Adapalene, Benzoyl Peroxide Gel

Intervention Type DRUG

Adapalene 1mg/g, Benzoyl Peroxide 25mg/ml

Interventions

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Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule

Lactobacillus Rhamnosus 1,5 х 10\*9, Inulin 25mg, D-chiro-inositol 250mg

Intervention Type DIETARY_SUPPLEMENT

Topical Adapalene, Benzoyl Peroxide Gel

Adapalene 1mg/g, Benzoyl Peroxide 25mg/ml

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients with mild to moderate level of Acne Vulgaris

Exclusion Criteria

* Pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

27 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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delta medical promotions ag

UNKNOWN

Sponsor Role collaborator

Treatment and Diagnostic Center of Private Enterprise "Asklepiy"

OTHER

Sponsor Role lead

Responsible Party

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Yuriy Andrashko

Yuriy Andrashko

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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TDC PE "Asklepiy"

Uzhhorod, Zakarpattia Oblast, Ukraine

Site Status

Countries

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Ukraine

Other Identifiers

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EDA1370

Identifier Type: -

Identifier Source: org_study_id

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