Study of Wellness Behaviors as a Function of Oxytocin vs Placebo
NCT ID: NCT01929161
Last Updated: 2016-07-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1
239 participants
INTERVENTIONAL
2013-09-30
2014-09-30
Brief Summary
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The proposed research targets three hypotheses: (1) Oxytocin manipulation magnifies (i.e., moderates) the positive emotion yield of Lovingkindness meditation; (2) The positive emotion yield of meditation, which varies by experimental condition, increases the nonconscious incentive salience of Wellness Behavior-related cues; and (3) Behavioral decisions predict positive emotions, sparking the relationships among OT manipulation, positive emotion yield, and nonconscious incentive salience of Wellness Behavior-related cues.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
FACTORIAL
BASIC_SCIENCE
DOUBLE
Study Groups
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Oxytocin
Oxytocin intranasal spray, 6 intranasal sufflations which deliver a total of 24 international units of oxytocin
Oxytocin
24 International Units
Lovingkindness Meditation
Mindfulness Meditation
Placebo (for oxytocin)
Intranasal spray with all equivalent ingredients except oxytocin
Placebo (for oxytocin)
intranasal spray manufactured to mimic oxytocin nasal spray
Lovingkindness Meditation
Mindfulness Meditation
Lovingkindness Meditation
Lovingkindness guided meditation experienced in the laboratory and 6 additional LKM meditations taken home on the iPod.
Oxytocin
24 International Units
Placebo (for oxytocin)
intranasal spray manufactured to mimic oxytocin nasal spray
Lovingkindness Meditation
Mindfulness Meditation
Mindfulness guided meditation experienced in the laboratory and 6 additional Mindfulness meditations taken home on the iPod.
Oxytocin
24 International Units
Placebo (for oxytocin)
intranasal spray manufactured to mimic oxytocin nasal spray
Mindfulness Meditation
Interventions
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Oxytocin
24 International Units
Placebo (for oxytocin)
intranasal spray manufactured to mimic oxytocin nasal spray
Lovingkindness Meditation
Mindfulness Meditation
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Fluent in written and spoken English
* Willingness or interest in learning to meditate
* Computer literate with access to internet (weekly)
Exclusion Criteria
* Individuals on antihypertensive medication
* Individuals who have or have had a regular meditation practice
* Individuals who can read Chinese logographs
35 Years
64 Years
ALL
Yes
Sponsors
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National Institute of Nursing Research (NINR)
NIH
University of North Carolina, Chapel Hill
OTHER
Responsible Party
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Barbara L. Fredrickson, PhD
Kenan Distinguished Professor
Principal Investigators
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Barbara L Fredrickson, Ph.D.
Role: PRINCIPAL_INVESTIGATOR
University of North Carolina, Chapel Hill
Locations
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UNC PEP Lab
Chapel Hill, North Carolina, United States
Countries
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Other Identifiers
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12-2371 IRB
Identifier Type: -
Identifier Source: org_study_id
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