The Role of Tranexamic Acid in Reducing Blood Transfusion Requirements After Cardiopulmonary Bypass in Neonates
NCT ID: NCT01914211
Last Updated: 2017-02-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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WITHDRAWN
OBSERVATIONAL
2013-07-31
2014-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Acute Normovolemic Hemodilution
Patients that receive acute normovolemic hemodilution prior to surgery.
Acute Normovolemic Hemodilution
Draw 20 mL/kg (up to 5Kg) of blood from patient and replace with washed PRBCs at 10-20mL/kg. (If \> 5Kg draw 20% of circulating blood volume without PRBC replacement)
Tranexamic Acid
Patients that receive tranexamic acid during surgery.
Tranexamic Acid
100mg/kg prior to incision, 100mg/kg on CPB and 100mg/kg after reversal of heparin with protamine.
Interventions
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Tranexamic Acid
100mg/kg prior to incision, 100mg/kg on CPB and 100mg/kg after reversal of heparin with protamine.
Acute Normovolemic Hemodilution
Draw 20 mL/kg (up to 5Kg) of blood from patient and replace with washed PRBCs at 10-20mL/kg. (If \> 5Kg draw 20% of circulating blood volume without PRBC replacement)
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
28 Days
ALL
No
Sponsors
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Aymen N Naguib
OTHER
Responsible Party
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Aymen N Naguib
Director of Pediatric Cardiothoracic Anesthesia
Locations
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Nationwide Children's Hospital
Columbus, Ohio, United States
Countries
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Other Identifiers
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IRB13-00350
Identifier Type: -
Identifier Source: org_study_id
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