Persistent Atrial Fibrillation Ablation Trial

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

SUSPENDED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-09-30

Study Completion Date

2016-09-30

Brief Summary

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Persistent atrial fibrillation (AF) is a common and distressing condition, that can cause significant symptoms. AF ablation is a recognised technique to treat persistent AF, but can be technically difficult. This study compares percutaneous ablation to thoracoscopic surgical AF ablation.

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Detailed Description

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Conditions

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Atrial Fibrillation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Pecutaneous AF ablation

Percutaneous catheter ablation of atrial fibrillation

Group Type ACTIVE_COMPARATOR

Percutaneous AF ablation

Intervention Type PROCEDURE

Percutaneous catheter ablation of atrial fibrillation

Surgical AF ablation

Minimally invasive thoracoscopic surgical ablation of atrial fibrillation

Group Type ACTIVE_COMPARATOR

Surgical AF ablation

Intervention Type PROCEDURE

Minimally invasive thoracoscopic surgical ablation of atrial fibrillation

Interventions

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Surgical AF ablation

Minimally invasive thoracoscopic surgical ablation of atrial fibrillation

Intervention Type PROCEDURE

Percutaneous AF ablation

Percutaneous catheter ablation of atrial fibrillation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Symptomatic persistent or long-standing AF suitable for AF ablation.
* Age over 18 years old.
* Informed consent to participate in this study.

Exclusion Criteria

* Pre-existing ILRs or permanent pacemakers that do not allow for continuous monitoring for AF occurrence, or are not MRI-safe.
* Unable to undergo general anaesthesia for AF ablation.
* Previous cardiac surgery, such as coronary artery bypass grafting or valvular surgery.
* Scheduled for elective cardiac surgery, such as coronary artery bypass grafting or valvular surgery.
* Previous thoracic surgery.
* Participation in a conflicting study.
* Potential participants who are mentally incapacitated and cannot consent or comply with follow-up
* Pregnancy
* Other cardiac rhythm disorders

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No