Mild Hypothermia in Cardiogenic Shock Complicating Myocardial Infarction
NCT ID: NCT01890317
Last Updated: 2018-07-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
40 participants
INTERVENTIONAL
2012-08-31
2016-03-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Mild hypothermia
Induction of mild hypothermia for 24 hr with invasive cooling in addition to primary percutaneous coronary intervention and optimal medical therapy
Mild hypothermia
Induction of mild hypothermia with invasive cooling for 24 hr in addition to primary percutaneous coronary intervention and optimal medical therapy.
Control
Percutaneous coronary intervention and optimal medical therapy according to current guidelines
No interventions assigned to this group
Interventions
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Mild hypothermia
Induction of mild hypothermia with invasive cooling for 24 hr in addition to primary percutaneous coronary intervention and optimal medical therapy.
Eligibility Criteria
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Inclusion Criteria
* Patients on mechanical ventilation at time of randomization
Exclusion Criteria
* mechanical complications after acute myocardial infarction
* duration of cardiogenic shock \> 12 hours
* age \> 90 years
18 Years
90 Years
ALL
No
Sponsors
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University of Leipzig
OTHER
Responsible Party
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Holger Thiele
Co-Director Clinic for Internal Medicine/Cardiology
Principal Investigators
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Holger Thiele, MD
Role: STUDY_CHAIR
Heart Center Leipzig - University Hospital
Georg Fuernau, MD
Role: PRINCIPAL_INVESTIGATOR
Heart Center Leipzig - University Hospital
Locations
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Department of Internal Medicine/Cardiology, University of Leipzig - Heart Center
Leipzig, Saxony, Germany
Countries
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References
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Cheng W, Fuernau G, Desch S, Freund A, Feistritzer HJ, Poss J, Buettner P, Thiele H. Circulating Monocyte Chemoattractant Protein-1 in Patients with Cardiogenic Shock Complicating Acute Myocardial Infarction Treated with Mild Hypothermia: A Biomarker Substudy of SHOCK-COOL Trial. J Cardiovasc Dev Dis. 2022 Aug 20;9(8):280. doi: 10.3390/jcdd9080280.
Fuernau G, Beck J, Desch S, Eitel I, Jung C, Erbs S, Mangner N, Lurz P, Fengler K, Jobs A, Vonthein R, de Waha-Thiele S, Sandri M, Schuler G, Thiele H. Mild Hypothermia in Cardiogenic Shock Complicating Myocardial Infarction. Circulation. 2019 Jan 22;139(4):448-457. doi: 10.1161/CIRCULATIONAHA.117.032722.
Other Identifiers
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HZLCOOL1
Identifier Type: -
Identifier Source: org_study_id
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