Effectiveness of Low Energy Laser Treatment in Oral Mucositis Induced by Chemotherapy and Radiotherapy in Head and Neck Cancer

NCT ID: NCT01876407

Last Updated: 2016-02-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

126 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-01-31

Study Completion Date

2016-07-31

Brief Summary

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The purpose of this study is to evaluate the effectiveness of using to low intensity laser as an intervention against preventive and therapeutic oral mucositis induced by radiotherapy and chemotherapy.

Detailed Description

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Conditions

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Oral Mucositis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Low energy laser

Administration of a low energy laser for oral mucositis.

Group Type EXPERIMENTAL

Low intensity laser for oral mucositis

Intervention Type DEVICE

Placebo

Group Type PLACEBO_COMPARATOR

Low intensity laser for oral mucositis switch off

Intervention Type DEVICE

Low intensity laser for oral mucositis switch off

Interventions

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Low intensity laser for oral mucositis

Intervention Type DEVICE

Low intensity laser for oral mucositis switch off

Low intensity laser for oral mucositis switch off

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients diagnosed with squamous cell carcinoma of the oral cavity.
* Patients aged between 18 and 80 years.
* Patients who are to receive one of the following treatment
* Combined radiotherapy (conventional fractionation 70 Gy reaching the tumor and affected lymph nodes, and 50 Gy in the areas ganglion drainage) and chemotherapy (cisplatin 100 mg/m2 IV on days 1, 22 and 43 irradiation or cetuximab 400mg/m2 as a single dose pre-load radiotherapy and 250mg/m2 weekly for the same. Regardless of whether they have received previous surgical treatment.
* Treatment with radiotherapy of 70 Gy in 35 daily sessions 2Gy/día consecutive.
* Patients who voluntarily express their intention to participate by informed consent.

Exclusion Criteria

* Patients who denied informed consent.
* Patients who have hypersensitivity or allergy to any of the components included in the study.
* Patients diagnosed with HIV, and autoimmune diseases.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fundación Pública Andaluza Progreso y Salud

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Daniel Torres Lagares

Role: PRINCIPAL_INVESTIGATOR

Hospitales Universitarios Virgen del Rocío

Locations

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Hospital Universitario Virgen del Rocío

Seville, , Spain

Site Status RECRUITING

Countries

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Spain

Central Contacts

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Daniel Torres Lagares

Role: CONTACT

María del Mar Benjumea Vargas

Role: CONTACT

955 04 04 50

Facility Contacts

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Daniel Torres Lagares

Role: primary

Other Identifiers

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001001006001

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

FPS-LAS-2012-04

Identifier Type: -

Identifier Source: org_study_id

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