OPtical Frequency Domain Imaging Versus INtravascular Ultrasound in Percutaneous Coronary InterventiON - OPINION Imaging

NCT ID: NCT01873222

Last Updated: 2016-07-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

106 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-06-30

Study Completion Date

2016-07-31

Brief Summary

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This study is the sub-study of OPINION Trial. (UMIN000010580) The aim of this study is to evaluate how Optical frequency domain imaging (OFDI) or Intravascular Ultrasound (IVUS) imaging technology influence to the Percutaneous Coronary Intervention (PCI) strategy.

Detailed Description

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Optical frequency domain imaging (OFDI) is a novel, high resolution intravascular imaging modality. Intravascular ultrasound (IVUS) is a widely used conventional imaging modality for achieving optimal stent deployment.

This study is the sub-study of OPINION Trial. (UMIN000010580) The aim of this study is to evaluate how OFDI or IVUS imaging technology influence to the Percutaneous Coronary Intervention (PCI) strategy.

We will enroll the first 100 patients who have enrolled in the main-study of OPINION trial.(UMIN000010580). We will assess lesions by the other device in addition to the assigned device in the main study at the time of post-PCI.

We will then assess lesions by OFDI at a 8-month follo-up.

Conditions

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Coronary Artery Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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OFDI-guided PCI & IVUS

* Assessment by IVUS at post-PCI
* Assessment by OFDI at a 8-month follow-up

Group Type EXPERIMENTAL

OFDI-guided PCI & IVUS

Intervention Type DEVICE

* Assessment by IVUS at post-PCI
* Assessment by OFDI at a 8-month follow-up

IVUS-guided PCI & OFDI

* Assessment by OFDI at post-PCI
* Assessment by OFDI at a 8-month follow-up

Group Type ACTIVE_COMPARATOR

IVUS-guided PCI & OFDI

Intervention Type DEVICE

* Assessment by OFDI at post-PCI
* Assessment by OFDI at a 8-month follow-up

Interventions

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OFDI-guided PCI & IVUS

* Assessment by IVUS at post-PCI
* Assessment by OFDI at a 8-month follow-up

Intervention Type DEVICE

IVUS-guided PCI & OFDI

* Assessment by OFDI at post-PCI
* Assessment by OFDI at a 8-month follow-up

Intervention Type DEVICE

Other Intervention Names

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OFDI LUNAWAVE Biolimus A9-eluting stent (Nobori stent) VISIWAVE ViewIT Biolimus A9-eluting stent (Nobori stent)

Eligibility Criteria

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Inclusion Criteria

* Patients participating in the OPINION Trial
* Patients who has provided written informed consent

Exclusion Criteria

* Ineligible patients according to the investigator's judgment
* Inability or unwillingness to perform required follow up procedures
Minimum Eligible Age

20 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wakayama Medical University

OTHER

Sponsor Role collaborator

Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Takashi Akasaka, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Wakayama Medical University

Locations

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Wakayama Medical University

Wakayama, Wakayama, Japan

Site Status

Countries

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Japan

References

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Otake H, Kubo T, Takahashi H, Shinke T, Okamura T, Hibi K, Nakazawa G, Morino Y, Shite J, Fusazaki T, Kozuma K, Ioji T, Kaneda H, Akasaka T; OPINION Investigators. Optical Frequency Domain Imaging Versus Intravascular Ultrasound in Percutaneous Coronary Intervention (OPINION Trial): Results From the OPINION Imaging Study. JACC Cardiovasc Imaging. 2018 Jan;11(1):111-123. doi: 10.1016/j.jcmg.2017.06.021. Epub 2017 Oct 5.

Reference Type DERIVED
PMID: 28917678 (View on PubMed)

Other Identifiers

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UMIN000010581

Identifier Type: REGISTRY

Identifier Source: secondary_id

TRICVD1311

Identifier Type: -

Identifier Source: org_study_id

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