The Role of Clinical Pharmacist in Management of DDIs in CHF Patients

NCT ID: NCT01855165

Last Updated: 2013-05-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-04-30

Study Completion Date

2013-12-31

Brief Summary

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Drug-drug interactions (DDIs) are common in patients with chronic heart failure (CHF) and their incidence increases with the number of drugs that the patients are prescribed for treatment of their condition. Data bases often detect DDIs that are of high clinical relevance. The investigators have performed this study in order to detect clinically significant DDIs and to diminish their occurrence by sending notification about DDIs to attending physician.

Detailed Description

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Conditions

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Chronic Heart Failure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Advice on DDIs

Attending physician will be randomly assigned to intervention arm care as usual; in the intervention arm, he/she will receive advice about DDIs between medications prescribed to patients on top of general heart failure advice.

Group Type EXPERIMENTAL

Advice on DDIs

Intervention Type BEHAVIORAL

General advice

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Advice on DDIs

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Patients admitted with diagnosis of CHF I50.0 - I50.9 and I11.0 - I11.9 (ICD-10)
* patients treated with at least two drugs

Exclusion Criteria

* Patients admitted to other conditions
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The University Clinic of Pulmonary and Allergic Diseases Golnik

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mitja Lainscak, PhD

Role: PRINCIPAL_INVESTIGATOR

University Clinic Golnik

Locations

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University Clinic Golnik

Golnik, , Slovenia

Site Status RECRUITING

Countries

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Slovenia

Central Contacts

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Mitja Lainscak, PhD

Role: CONTACT

+38642569141

Facility Contacts

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Mitja Lainscak, Md, PhD

Role: primary

+38642569141

References

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Roblek T, Deticek A, Leskovar B, Suskovic S, Horvat M, Belic A, Mrhar A, Lainscak M. Clinical-pharmacist intervention reduces clinically relevant drug-drug interactions in patients with heart failure: A randomized, double-blind, controlled trial. Int J Cardiol. 2016 Jan 15;203:647-52. doi: 10.1016/j.ijcard.2015.10.206. Epub 2015 Oct 28.

Reference Type DERIVED
PMID: 26580349 (View on PubMed)

Other Identifiers

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109/01/13

Identifier Type: OTHER

Identifier Source: secondary_id

CHF42013

Identifier Type: -

Identifier Source: org_study_id

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