Repetitive Transcranial Magnetic Stimulation for Freezing of Gait

NCT ID: NCT01853150

Last Updated: 2018-07-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-04-30

Study Completion Date

2018-07-31

Brief Summary

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Freezing of gait (FOG) means that patients cannot walk without any known causes, other than parkinsonism, which is very disabling symptom. Patients descirbe their feeling of the feet suddenly being glued to the floor. Transcranial magnetic stiumation is a noninvasive procedure using electromagnetic induction to stimulate brain. Transcranial magnetic stiumation (rTMS) can selectively change brain activity to enhance desired effects. The aim of this study is to the therapeutic effect of rTMS for the FOG.

Detailed Description

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Conditions

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Parkinsonian Disorders

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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rTMS Motor cortex

rTMS will be applied over the motor cortex

Group Type EXPERIMENTAL

rTMS Motor cortex

Intervention Type DEVICE

rTMS Supplementary motor area

rTMS will be applied over the supplementary motor area

Group Type ACTIVE_COMPARATOR

rTMS Supplementary motor area

Intervention Type DEVICE

Interventions

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rTMS Motor cortex

Intervention Type DEVICE

rTMS Supplementary motor area

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Parkinson's disease or Primary progressive freezing of gait
* age 18 and older
* Freezing of gait

Exclusion Criteria

* pregnant or any, other medical, surgical, neurological or psychiatric conditions
* other restrictions which prevent you from undergoing TMS recording, such as; surgically or traumatically implanted foreign bodies such as a pacemaker, an implanted medication pump, a metal plate in the skull, or metal inside the skull or eyes (other than dental appliances or fillings), and/ or heart/cardiac lines
* any past or current history of seizure disorder or epilepsy
* unable to give informed consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Dongtan Sacred Heart Hospital

OTHER

Sponsor Role lead

Responsible Party

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Suk Yun Kang

MD, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Dongtan Sacred Heart Hospital

Hwaseong-si, Gyeonggi-do, South Korea

Site Status

Countries

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South Korea

Other Identifiers

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2013-022

Identifier Type: -

Identifier Source: org_study_id

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