Effects of Brain Stimulation During Daytime Nap on Memory Consolidation in Younger, Healthy Subjects
NCT ID: NCT01840865
Last Updated: 2016-03-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
22 participants
INTERVENTIONAL
2013-10-31
2015-01-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
TRIPLE
Study Groups
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SHAM stimulation
SHAM stimulation during periods of Slow Wave Sleep
no stimulation
sham Stimulation
0,75 Hz stimulation
slow transcranial oscillating stimulation (\~0,75Hz) during periods of Slow Wave Sleep
brain stimulation
oscillating direct current brain stimulation
Interventions
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brain stimulation
oscillating direct current brain stimulation
no stimulation
sham Stimulation
Eligibility Criteria
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Inclusion Criteria
* unobtrusive, neuropsychological screening
* age: 18-35 years
* right handed
Exclusion Criteria
* epilepsy
* other severe neurological diseases eg., previous major stroke, brain tumour
* contraindications to MRI
18 Years
35 Years
ALL
Yes
Sponsors
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Charite University, Berlin, Germany
OTHER
Responsible Party
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Agnes Flöel
Prof. Agnes Flöel, MD
Principal Investigators
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Agnes Flöel, Professor
Role: PRINCIPAL_INVESTIGATOR
Charite Universitätsmedizin Berlin - Neurologie
Locations
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Charite CCM Neurologie Berlin
Berlin, State of Berlin, Germany
Countries
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References
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Marshall L, Helgadottir H, Molle M, Born J. Boosting slow oscillations during sleep potentiates memory. Nature. 2006 Nov 30;444(7119):610-3. doi: 10.1038/nature05278. Epub 2006 Nov 5.
Diekelmann S, Born J. The memory function of sleep. Nat Rev Neurosci. 2010 Feb;11(2):114-26. doi: 10.1038/nrn2762. Epub 2010 Jan 4.
Mednick SC, Cai DJ, Kanady J, Drummond SP. Comparing the benefits of caffeine, naps and placebo on verbal, motor and perceptual memory. Behav Brain Res. 2008 Nov 3;193(1):79-86. doi: 10.1016/j.bbr.2008.04.028. Epub 2008 May 8.
Mander BA, Santhanam S, Saletin JM, Walker MP. Wake deterioration and sleep restoration of human learning. Curr Biol. 2011 Mar 8;21(5):R183-4. doi: 10.1016/j.cub.2011.01.019. No abstract available.
Mednick S, Nakayama K, Stickgold R. Sleep-dependent learning: a nap is as good as a night. Nat Neurosci. 2003 Jul;6(7):697-8. doi: 10.1038/nn1078.
Ladenbauer J, Ladenbauer J, Kulzow N, Floel A. Memory-relevant nap sleep physiology in healthy and pathological aging. Sleep. 2021 Jul 9;44(7):zsab002. doi: 10.1093/sleep/zsab002.
Other Identifiers
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Nap-tSOS-young
Identifier Type: -
Identifier Source: org_study_id
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