40 Hz Transcranial Alternating Current Stimulation for Inducing Gamma Oscillations
NCT ID: NCT06740864
Last Updated: 2024-12-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
30 participants
INTERVENTIONAL
2024-06-01
2025-06-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
DOUBLE
Study Groups
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40 Hz prefrontal Transcranial alternating current stimulation
During prefrontal tACS, an alternating electrical current with a 1 milliamp peak-to-peak amplitude will be delivered, featuring a 15-second ramp-up at the start and a 15-second ramp-down at the end. The stimulation duration is 20 minutes and four channels are used for delivering sinusoidal alternating currents to the head. The alternating current was delivered to the prefrontal cortex bilaterally with the electrodes at F3 and F4 and the return electrodes were placed at the ipsilateral mastoids at TP9 and TP10 (international 10-20 EEG electrode placement system).
Transcranial alternating current stimulation
Transcranial alternating current will be delivered utilizing a Starstim 8-channel constant current, battery-powered electric stimulator (Neuroelectrics, Barcelona, Spain). Circular carbon rubber electrodes (2cm radius, 12,57 cm2) are used throughout the stimulation.
40 Hz frontal-temporal Transcranial alternating current stimulation
During frontal-temporal tACS, an alternating electrical current with a personalized peak-to-peak stimulation intensity will be delivered, featuring a 15-second ramp-up at the start and a 15-second ramp-down at the end. The stimulation duration is 20 minutes and four channels are used for delivering sinusoidal alternating currents to the head. The alternating current was delivered to the prefrontal and temporal cortices with the active electrodes at AF3-T7 and the return electrodes over AF4-T8 (according international 10-20 EEG electrode placement system).
Transcranial alternating current stimulation
Transcranial alternating current will be delivered utilizing a Starstim 8-channel constant current, battery-powered electric stimulator (Neuroelectrics, Barcelona, Spain). Circular carbon rubber electrodes (2cm radius, 12,57 cm2) are used throughout the stimulation.
sham Transcranial alternating current stimulation
During sham tACS, an alternating artificial electrical current will be delivered, only ramping the current for 15 seconds up and 15 seconds down at the beginning and end of the stimulation respectively.
Sham Transcranial alternating current stimulation
Sham tACS will be applied by only ramping the current for 15 seconds up and 15 seconds down at the beginning and end of the stimulation respectively.
Interventions
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Transcranial alternating current stimulation
Transcranial alternating current will be delivered utilizing a Starstim 8-channel constant current, battery-powered electric stimulator (Neuroelectrics, Barcelona, Spain). Circular carbon rubber electrodes (2cm radius, 12,57 cm2) are used throughout the stimulation.
Transcranial alternating current stimulation
Transcranial alternating current will be delivered utilizing a Starstim 8-channel constant current, battery-powered electric stimulator (Neuroelectrics, Barcelona, Spain). Circular carbon rubber electrodes (2cm radius, 12,57 cm2) are used throughout the stimulation.
Sham Transcranial alternating current stimulation
Sham tACS will be applied by only ramping the current for 15 seconds up and 15 seconds down at the beginning and end of the stimulation respectively.
Eligibility Criteria
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Inclusion Criteria
* normal or corrected to normal eye vision
* right-handed
* non-smokers
* at least 70 % accuracy in working memory training task
Exclusion Criteria
* Taking CNS, blood pressure and other medications
* having metal implants in the head and neck
* significant cognitive decline meassured by The Montreal Cognitive Assessment (MoCA)
50 Years
85 Years
ALL
Yes
Sponsors
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Technical University of Dortmund
OTHER
Leibniz Research Centre for Working Environment and Human Factors
OTHER
Institute for Research in Fundamental Sciences (IPM)
UNKNOWN
The National Brain Mapping Laboratory (NBML)
OTHER
Responsible Party
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Mohammad Ali Salehinejad
Principal Investigator
Locations
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Institute for Research in Fundamental Sciences
Tehran, , Iran
Countries
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Central Contacts
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Facility Contacts
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Mohammad Ali Salehinejad, PhD
Role: primary
Other Identifiers
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IfADo_196_P3
Identifier Type: -
Identifier Source: org_study_id