DETECT and Retinal Outcomes in Hypertension

NCT ID: NCT01815567

Last Updated: 2021-05-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

234 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-11-30

Study Completion Date

2020-07-15

Brief Summary

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The purpose of this study is to study the impact of blood pressure on cognitive performance.

Detailed Description

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Four groups will be evaluated for possible impact of blood pressure on cognitive performance and retinal damage.

Conditions

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Hypertension Retinal Disorder Cognitive Impairment

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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controlled hypertension

hypertension with medication controlled

No interventions assigned to this group

uncontrolled hypertension

non-controlled hypertension

No interventions assigned to this group

hypertensive urgency

hypertensive urgency no previous history or antihypertensives

No interventions assigned to this group

asymptomatic normotensive

asymptomatic normotensive control group

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Patients triaged to the Grady Memorial Hospital Emergency Department or Marcus Trauma Unit
2. Age \>18 and \<65
3. Documented history of hypertension plus one or more of the following:

* current antihypertensive use with controlled blood pressure
* elevated Emergency Department systolic blood pressure or diastolic blood pressure
* OR -
4. Acutely elevated Emergency Department systolic blood pressure or diastolic blood pressure on 2 separate Emergency Department measurements in the absence of a history of hypertension

* OR -
5. Normal systolic blood pressure or diastolic blood pressure in the absence of hypertension.

Exclusion Criteria

1. Non-English speaking
2. Pre-visit cognitive impairment
3. Physical or psychological impairments that would prohibit comprehension and completion of DETECT testing
4. Inability to obtain adequate fundoscopic photos
5. Acute intoxication, altered mental status, or head injury within the last 6 months
6. Opiate or benzodiazepine administration by treating providers
7. Clinical condition not allowing testing.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Emory University

OTHER

Sponsor Role lead

Responsible Party

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Tamara Espinoza, MD

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Tamara Espinoza, MD

Role: PRINCIPAL_INVESTIGATOR

Emory University

Locations

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Grady Memorial Hospital

Atlanta, Georgia, United States

Site Status

Countries

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United States

Other Identifiers

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IRB00060043

Identifier Type: -

Identifier Source: org_study_id

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