Cardiac Function in Severe Aneurysmal Subarachnoid Haemorrhage Patients

NCT ID: NCT01801800

Last Updated: 2014-05-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-01-31

Study Completion Date

2013-12-31

Brief Summary

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Cardiac dysfunction can occur in aneurysmal subarachnoid haemorrhage and might impact patient's neurologic outcome Condition Aneurysmal subarachnoid haemorrhage World Neurosurgeon Federation Score ≥ III

Detailed Description

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Trans-thoracic echocardiography on day 1, day 3 and day 7 Speckle-Tracking of echocardiographic loops by a cardiologist blinded to the patient's management and outcome

Conditions

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Aneurysmal Subarachnoid Haemorrhage World Neurosurgeon Federation Score ≥ III

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Aneurysmal subarachnoid haemorrhage

Speckle-tracking images in Echocardiography

Echocardiography

Intervention Type PROCEDURE

Speckle-Tracking of echocardiographic loops by a cardiologist blinded to the patient's management and outcome

Interventions

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Echocardiography

Speckle-Tracking of echocardiographic loops by a cardiologist blinded to the patient's management and outcome

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Aneurysmal subarachnoid haemorrhage
* World Neurosurgeon Federation Score ≥ III
* Written information to next-of-kin and patients when possible

Exclusion Criteria

* History of myocardial infarction, chronic heart failure with NYHA ≥ 2, major heart surgery
* Lack of acoustic window to perform trans-thoracic echocardiography
Minimum Eligible Age

15 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Nantes University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Raphael Cinotti, MD

Role: PRINCIPAL_INVESTIGATOR

Nantes University Hospital

Bertrand ROZEC, PhD, MD

Role: STUDY_CHAIR

Nantes University Hospital

Locations

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University Hospital

Nantes, , France

Site Status

University Hospital

Rennes, , France

Site Status

Countries

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France

References

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Hofmeijer J, Kappelle LJ, Algra A, Amelink GJ, van Gijn J, van der Worp HB; HAMLET investigators. Surgical decompression for space-occupying cerebral infarction (the Hemicraniectomy After Middle Cerebral Artery infarction with Life-threatening Edema Trial [HAMLET]): a multicentre, open, randomised trial. Lancet Neurol. 2009 Apr;8(4):326-33. doi: 10.1016/S1474-4422(09)70047-X. Epub 2009 Mar 5.

Reference Type BACKGROUND
PMID: 19269254 (View on PubMed)

Other Identifiers

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RC12_0410

Identifier Type: -

Identifier Source: org_study_id

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