Self-Selection and Actual Use Trial of Ibuprofen 600 mg Immediate Release/Extended Caplet

NCT ID: NCT01789606

Last Updated: 2017-08-28

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

1083 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-09-24

Study Completion Date

2013-06-03

Brief Summary

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A self-selection and actual use trial to evaluate the extent to which consumers will appropriately select and use the 600 mg immediate release/extended release caplets and comply with dosing instructions.

Detailed Description

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Conditions

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Analgesia

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Ibuprofen 600 mg Immediate Release/Extended Release Caplet

Group Type EXPERIMENTAL

Ibuprofen 600 mg Immediate Release/Extended Release Caplet

Intervention Type DRUG

Ibuprofen 600 mg Immediate Release/Extended Release Caplet to be adminstered orally (i.e., one caplet every 12 hours, not to exceed 2 caplets per day) for pain.

Interventions

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Ibuprofen 600 mg Immediate Release/Extended Release Caplet

Ibuprofen 600 mg Immediate Release/Extended Release Caplet to be adminstered orally (i.e., one caplet every 12 hours, not to exceed 2 caplets per day) for pain.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* at least 12 years of age
* use of at least 5 doses per month of over-the-counter pain relievers over the past 3 months
* provide written informed consent (subjects 12-\<18 years of age provide a written assent and parent/guardian will provide written informed consent)
* capable of and willing to swallow the study medication

Exclusion Criteria

* participated in other research studies in the last 6 months
* they or someone else in their household work for a pharmaceutical company, is a relative of study site personnel involved with the study, or an immediate family member is already enrolled in the study
* have a history of known allergies to ibuprofen, aspirin, or other NSAIDs
* have a history of heart surgery in the last 60 days or planned heart surgery in the next 60 days
* female subjects are pregnant or breast feeding
Minimum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Pfizer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pfizer CT.gov Call Center

Role: STUDY_DIRECTOR

Pfizer

Locations

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Medical Arts Rexall Pharmacy

Anaheim, California, United States

Site Status

B and B Pharmacy

Yorba Linda, California, United States

Site Status

Wynn's Pharmacy Inc.

Griffin, Georgia, United States

Site Status

Stark Pharmacy

Overland Park, Kansas, United States

Site Status

Catonsville Pharmacy

Baltimore, Maryland, United States

Site Status

Goodrich Pharmacy

Blaine, Minnesota, United States

Site Status

Kemper Drug

Elk River, Minnesota, United States

Site Status

Cub Pharmacy Number 1924

Saint Louis Park, Minnesota, United States

Site Status

Albers' Medical Pharmacy

Kansas City, Missouri, United States

Site Status

Countryside Pharmacy

Savannah, Missouri, United States

Site Status

Duran Central Pharmacy

Albuquerque, New Mexico, United States

Site Status

Total Health and Wellness Center of Taos

Taos, New Mexico, United States

Site Status

The Medicine Shoppe

Ogden, Utah, United States

Site Status

The Medicine Shoppe

Salt Lake City, Utah, United States

Site Status

Family Plaza Pharmacy

West Jordan, Utah, United States

Site Status

Montpelier Pharmacy, Inc.

Montpelier, Virginia, United States

Site Status

Ostrom Drugs

Kenmore, Washington, United States

Site Status

Kusler's Pharmacy

Snohomish, Washington, United States

Site Status

Countries

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United States

References

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Paluch E, Jayawardena S, Wilson B, Farnsworth S. Consumer self-selection, safety, and compliance with a novel over-the-counter ibuprofen 600-mg immediate-release and extended-release tablet. J Am Pharm Assoc (2003). 2016 Jul-Aug;56(4):397-404. doi: 10.1016/j.japh.2016.03.003. Epub 2016 May 13.

Reference Type DERIVED
PMID: 27184785 (View on PubMed)

Related Links

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Other Identifiers

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AK-10-11

Identifier Type: OTHER

Identifier Source: secondary_id

B4371008

Identifier Type: -

Identifier Source: org_study_id

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