Influence of a Single Dose Dexamethasone on the Time Course of Neuromuscular Blockade of Rocuronium
NCT ID: NCT01782820
Last Updated: 2022-08-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
108 participants
OBSERVATIONAL
2011-12-31
2013-01-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CROSSOVER
PROSPECTIVE
Study Groups
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dexamethasone late
dexamethasone during induction of anesthesia
No interventions assigned to this group
no dexamethasone
no dexamethasone during measurements
No interventions assigned to this group
dexamethasone early
dexamethasone before induction of anesthesia
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* American Society of Anesthesiologists Physical Status I or II,
* 50-90 kg body weight,
* undergoing elective laparoscopic gynaecological surgery in general anaesthesia necessitating intraoperative neuromuscular blockade.
Exclusion Criteria
* reduced opening of the mouth (\< 2cm), and Mallampati Score of 4),
* increased risk of pulmonary aspiration (gastrooesophageal reflux, full stomach, intestinal obstruction),
* known allergies to the drugs tested,
* pregnancy,
* neuromuscular disorders,
* intake of drugs affecting neuromuscular blockade, such as furosemide, magnesium or cephalosporins,
* hepatic-or renal insufficiency.
18 Years
65 Years
FEMALE
No
Sponsors
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Kreiskrankenhaus Dormagen
OTHER
Responsible Party
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Locations
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Kreiskrankenhaus Dormagen
Dormagen, , Germany
Countries
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References
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Soltesz S, Fraisl P, Noe KG, Hinkelbein J, Mellinghoff H, Mencke T. Dexamethasone decreases the duration of rocuronium-induced neuromuscular block: a randomised controlled study. Eur J Anaesthesiol. 2014 Aug;31(8):417-22. doi: 10.1097/EJA.0b013e328365c9ee.
Other Identifiers
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dexarelax
Identifier Type: -
Identifier Source: org_study_id
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