An Investigation of Light Therapy for Cancer-related Fatigue (The LITE Study)

NCT ID: NCT01780623

Last Updated: 2016-04-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

88 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-01-31

Study Completion Date

2015-04-30

Brief Summary

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Cancer-related fatigue is one of the most common and distressing symptoms associated with a cancer diagnosis.Fatigue related to cancer often appears before a diagnosis, worsens during treatment, and lasts for years after treatment in up to 35% of patients. Despite the long-term effects of cancer-related fatigue, the treatment options available are not always appropriate or helpful for all patients.Light therapy is an effective treatment for other disorders related to fatigue. The purpose of the study is to investigate the role of light therapy on quality of life, sleep patterns, and physical measures of immune function and stress hormones in individuals with post-treatment cancer-related fatigue.

Detailed Description

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Conditions

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Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Bright White Light

Bright white light exposure every morning for 30 minutes for 28 consecutive days

Group Type EXPERIMENTAL

Bright white light

Intervention Type DEVICE

Dim Red Light

Dim red light exposure every morning for 30 minutes for 28 consecutive days

Group Type ACTIVE_COMPARATOR

Dim red light

Intervention Type DEVICE

Interventions

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Bright white light

Intervention Type DEVICE

Dim red light

Intervention Type DEVICE

Other Intervention Names

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Light box LiteBook Light box LiteBook

Eligibility Criteria

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Inclusion Criteria

* English speaking
* Non metastatic cancer
* At least 3 months post chemotherapy/radiation treatment (hormone treatment ok)
* Meets criteria for cancer-related fatigue

Exclusion Criteria

* Under 18 years of age
* Presence of a sleep disorder other than insomnia or hypersomnia
* Shift work
* Presence of an Axis-I psychiatric condition
* Presence of a medical condition that may impact levels of fatigue
* Presence of conditions contraindicated to the use of light therapy or photosensitizing medications
* Randomization refusal
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Canadian Cancer Society (CCS)

OTHER

Sponsor Role collaborator

University of Calgary

OTHER

Sponsor Role lead

Responsible Party

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Tavis S. Campbell

Dr. Tavis S. Campbell

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Tavis S Campbell, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Calgary

Locations

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Behavioural Medicine Laboratory

Calgary, Alberta, Canada

Site Status

Countries

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Canada

References

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Johnson JA, Subnis U, Carlson LE, Garland SN, Santos-Iglesias P, Piedalue KL, Deleemans JM, Campbell TS. Effects of a light therapy intervention on diurnal salivary cortisol in fatigued cancer survivors: A secondary analysis of a randomized controlled trial. J Psychosom Res. 2020 Dec;139:110266. doi: 10.1016/j.jpsychores.2020.110266. Epub 2020 Oct 6.

Reference Type DERIVED
PMID: 33070045 (View on PubMed)

Other Identifiers

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10003569

Identifier Type: -

Identifier Source: org_study_id

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