Diffusion MRI and Growth Plate Injuries: Pilot Study

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

10 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-11-30

Study Completion Date

2017-02-28

Brief Summary

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Children who suffer fractures to the growth plates (physes) of their bones are at risk for premature growth arrest which can lead to long term complications. There is currently no technique to predict who is at risk of growth arrest following a physeal injury. The investigators aim to determine if diffusion MRI (an imaging method to analyze tissue properties) can effectively pick up differences between a healthy growth plate and an injured one. This would allow orthopaedics surgeons to predict which injuries are at a higher risk of growth arrest, so earlier interventions can be done in the orthopaedic clinic.

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Detailed Description

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The purpose of this study is to determine if diffusion MRI can be used for tissue characterization in childhood and adolescent growth plate injuries, and to get a better understanding of the physiologic disturbance of an injured physis

Conditions

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Fracture

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Physeal Injury - Distal Radius

Patients who suffer a physeal fracture of the distal radius will be scanned and compared to their healthy contralateral limb.

Diffusion MRI

Intervention Type OTHER

Each subject will undergo one diffusion MRI scan to identify characteristics of their physes

Interventions

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Diffusion MRI

Each subject will undergo one diffusion MRI scan to identify characteristics of their physes

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Salter-Harris Type II, III, or IV fracture through the distal radius
* Growth plates are open
* Ages 8-12
* Able to consent in English

Exclusion Criteria

* All fractures not sustained to distal radius
* SH Type I or V fracture
* Injury to contralateral limb
* Previous injury to distal radius
* Diseases known to alter bone healing or growth\]
* Contraindications to undergoing an MRI scan

Minimum Eligible Age

8 Years

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No