Pediatric Radio Frequency Coils Generic

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

75 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-07-31

Study Completion Date

2025-06-30

Brief Summary

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The purpose of this study is to evaluate and optimize advances in radio frequency (RF) coil magnetic resonance imaging (MRI) technology at Cincinnati Children's Hospital Medical Center (CCHMC).

Detailed Description

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Pediatric Magnetic resonance (MR) imaging techniques have been limited by the unavailability of specialized radio-frequency (RF) coils for pediatric imaging. Typically, MR coils are designed for general purpose adult imaging and lack the mechanical design, flexibility and high channel count needed for pediatric imaging. Furthermore, pediatric patients are often positioned decubitus or prone rather than supine. This makes coil positioning even more challenging and often results in images with low SNR and poor image quality. Many coils used in clinical practice have fixed dimensions that do not fit within the realm of "one-size fits all," especially for the huge variation found in the pediatric patient population.

MRI coil development and optimization is performed by MR manufacturers and in research laboratories across the world including the Imaging Research Center (IRC) of Cincinnati Children's Hospital and Medical Center (CCHMC). Coil development and refinement involves evaluating the new coils on inert phantoms and then imaging examinations performed on healthy participants and patients. The focus of this study protocol is to evaluate the design and performance of investigational coils on patients and healthy participants.

Conditions

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Duchenne Muscular Dystrophy Musculoskeletal Abnormalities

Keywords

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Magnetic Resonance Imaging

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Advances in Radio Frequency for MRI

advances in radio frequency (RF) coil magnetic resonance imaging (MRI)

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

Healthy participants:

* Male or Female
* Thermally stable
* Any age

Clinical patients:

* Male or Female
* Thermally stable
* any age

Exclusion Criteria

Healthy participants \& Clinical patients

* Female participants who are pregnant or lactating
* Subjects iwth standard contraindications to MRI

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Charles Dumoulin, PhD

Role: PRINCIPAL_INVESTIGATOR

Children's Hospital Medical Center, Cincinnati

Locations

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Cincinnati Children's

Cincinnati, Ohio, United States

Site Status

Countries

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United States

Other Identifiers

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2012-1041

Identifier Type: -

Identifier Source: org_study_id