Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
42 participants
OBSERVATIONAL
2013-02-28
2014-06-30
Brief Summary
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Detailed Description
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Therefore the investigators plan to measure the levels of the paracetamol metabolites in patient undergoing liver resection.
Patients will undergo liver resection according to their onco-surgical requirements. As part of the normal post operative care they will receive 1g paracetamol every six hours unless stated otherwise by the operating surgeon. Urinary samples will be taken for the first 4 post operative days and used for analysis of the urinary paracetamol metabolite levels.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Liver resection group
Patients undergoing liver resection and receiving paracetamol (observation of routine administration)
Paracetamol (observation of routine administration)
Normal administration of paracetamol as prescribed by operating surgeon
Interventions
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Paracetamol (observation of routine administration)
Normal administration of paracetamol as prescribed by operating surgeon
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Inability to give written, informed consent.
* Jaundice (Bilirubin \> 100 μmol/L).
* Liver resection combined with secondary surgical procedure.
* Age \< 18 years.
* Pregnant women.
18 Years
ALL
No
Sponsors
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NHS Lothian
OTHER_GOV
University of Edinburgh
OTHER
Responsible Party
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Principal Investigators
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Michael J Hughes, MBChB
Role: PRINCIPAL_INVESTIGATOR
University of Edinburgh
Locations
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Royal Infirmary of Edinburgh
Edinburgh, Lothian, United Kingdom
Countries
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Other Identifiers
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12/SS/0222
Identifier Type: -
Identifier Source: org_study_id
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