Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

55 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-10-31

Brief Summary

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Adding dexamethasone to local anesthetic will significantly prolong duration of brachial plexus anesthesia and analgesia.

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Detailed Description

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Operations of upper extremities are often performed in regional anesthesia blocks. Single-injection blocks are effective, but time limited. Adding 4mg of dexamethasone to 0.5% levobupivacaine will significantly prolong duration of brachial plexus anesthesia and analgesia for fracture operations of upper extremity. This effect will result in less opioid use postoperatively.

Conditions

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Brachial Plexus Anesthesia Analgesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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dexamethasone with levobupivacaine

25ml 0.5% levobupivacaine plus 4mg Dexamethasone are given for supraclavicular brachial plexus block for upper extremity surgery

Group Type ACTIVE_COMPARATOR

supraclavicular brachial plexus block

Intervention Type PROCEDURE

levobupivacaine

25ml 0.5% levobupivacaine plus 1ml 0.9% saline are given for supraclavicular brachial plexus block for upper extremity surgery

Group Type ACTIVE_COMPARATOR

supraclavicular brachial plexus block

Intervention Type PROCEDURE

Interventions

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supraclavicular brachial plexus block

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* patients aged 18 years or older
* ASA (American Society of Anesthesiologists) physical status I, II or III

Exclusion Criteria

* refusal of the patients to give informed consent
* preexisting coagulation disorders
* local infection at the site of the block
* neuropathy
* drug or alcohol abusers
* known allergy to the drug used in study
* operation time exceeding six hours

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No