The Effect of Topical Lidocaine on Pain Scores During Manual Vacuum Aspiration for Nonviable Pregnancies

NCT ID: NCT01708330

Last Updated: 2016-07-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-10-31

Study Completion Date

2016-07-31

Brief Summary

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When a patient requires a manual vacuum aspiration (MVA), whether for an undesired pregnancy, missed abortion, or other nonviable pregnancy, she is undergoing an emotional experience. She is grieving the loss of her pregnancy, and is then faced with the anxiety of an invasive and often painful procedure. Minimizing the pain during this procedure must not be overlooked. There have been no randomized controlled trials evaluating pain control during MVA for nonviable pregnancy, and the data is mixed regarding analgesia for MVA for an elective abortion or other office procedures.

Women being treated at the Women \& Infants Triage who have experienced a first trimester missed abortion, inevitable abortion, incomplete abortion or other nonviable pregnancy and are being treated with an outpatient manual vacuum aspiration will be asked to enroll in this study. Those who wish to participate will be randomly assigned to treatment with lidocaine gel or a placebo gel applied to the cervix during their procedure.

The hypothesis is that topical lidocaine will decrease pain during manual vacuum aspiration.

Detailed Description

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Conditions

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Nonviable Pregnancy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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Placebo gel

Placebo gel applied topically to the cervix

Group Type PLACEBO_COMPARATOR

Placebo gel

Intervention Type DRUG

odorless, colorless gel will be used as a placebo

Lidocaine gel

2% lidocaine gel applied topically to the cervix

Group Type EXPERIMENTAL

Lidocaine

Intervention Type DRUG

2% Lidocaine gel

Interventions

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Lidocaine

2% Lidocaine gel

Intervention Type DRUG

Placebo gel

odorless, colorless gel will be used as a placebo

Intervention Type DRUG

Other Intervention Names

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KY Jelly

Eligibility Criteria

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Inclusion Criteria

* Patient at the Women and Infants Triage/Women's Emergency Department
* Vital signs are stable
* Ages 18 and older
* Have a missed abortion, inevitable abortion, incomplete abortion or other nonviable pregnancy
* Estimated gestational age up to 10 weeks
* Undergoing MVA at the Women and Infants Triage/Women's Emergency Department
* Able to read English or Spanish
* Able to give informed consent for involvement in the study

Exclusion Criteria

* Allergic to lidocaine, iodine or betadine
* Known sensitivity to any component of the lidocaine or placebo gel.
* In acute distress
* Unable to give informed consent
* Unable to read English or Spanish
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Women and Infants Hospital of Rhode Island

OTHER

Sponsor Role collaborator

Bridgeport Hospital

OTHER

Sponsor Role lead

Responsible Party

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Amanda Tower

Fellow

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Women and Infants Hospital Triage

Providence, Rhode Island, United States

Site Status

Countries

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United States

Other Identifiers

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12-0039

Identifier Type: -

Identifier Source: org_study_id

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