Ganglionated Plexi Ablation Combined With Pulmonary Vein Isolation
NCT ID: NCT01703247
Last Updated: 2012-10-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
264 participants
INTERVENTIONAL
2008-01-31
2009-05-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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PVI+LL
Circumferential PVI was accomplished and then additional ablation lines were created by connecting the left inferior PV to the mitral annulus (mitral isthmus) and the LA between the two superior PVs (roof). Finally, patients underwent cavo-tricuspid isthmus ablation in the right atrium.
Pulmonary vein isolation
Linear Lesion Ablation
PVI+GP
To accomplish ganglionated plexi ablation, LA target sites were identified as the anatomic locations where vagal reflexes were evoked by transcatheter high-frequency stimulation (HFS). Rectangular electrical stimuli were delivered at a frequency of 20-50 Hz, output amplitude 15 V and pulse duration of 10 ms, for 5 sec (Stimulator B-53, Biotok Inc, Russia).
Pulmonary vein isolation
Ganglionated plexi ablation
Interventions
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Pulmonary vein isolation
Ganglionated plexi ablation
Linear Lesion Ablation
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* LV ejection fraction \< 35%
* left atrial diameter \> 60 mm
18 Years
65 Years
ALL
No
Sponsors
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Meshalkin Research Institute of Pathology of Circulation
NETWORK
Responsible Party
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Principal Investigators
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Evgeny Pokushalov, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
State Research Institute of Circulation Pathology
Locations
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State Research Institute of CIrculation Pathology
Novosibirsk, , Russia
Countries
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Related Links
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State Research Institute of Circulation Pathology Official Site
Other Identifiers
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GP-LL-AF
Identifier Type: -
Identifier Source: org_study_id
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