Embryo Kinetics and Stimulation Protocol: Recombinant Follicle Stimulating Hormone (FSH) Versus Human FSH

NCT ID: NCT01678651

Last Updated: 2016-02-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-08-31

Study Completion Date

2013-02-28

Brief Summary

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Different kinetics markers have been proposed to select embryos with higher implantation rates. The effect of external factors on these markers, such as the stimulation protocol should be analyzed. There are two different types of FSH that are commonly used for in vitro fertilization (IVF) in egg donation cycles, recombinant FSH and human FSH. The effect of each kind of hormone on embryo kinetcis is still unknown. The aim of this study is to observe if there is a difference in embryo kinetics and morphology as well as oocyte morphological parameters between the two types of FSH and therefore to analyze if such markers can be used despite of the stimulation protocols chosen.

Detailed Description

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Conditions

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Embryo Kinetics

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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Human FSH

Human FSH

Group Type ACTIVE_COMPARATOR

Stimulation with human FSH

Intervention Type PROCEDURE

Human FSH

Recombinant FSH

Recombinant FSH

Group Type ACTIVE_COMPARATOR

Stimulation with recombinant FSH

Intervention Type PROCEDURE

Recombinant FSH

Interventions

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Stimulation with human FSH

Human FSH

Intervention Type PROCEDURE

Stimulation with recombinant FSH

Recombinant FSH

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

•Egg donation cycles with more than 8MII in oocyte retrieval day

Exclusion Criteria

* Male factor
* Uterine malformations
* genetic alterations
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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IVI Madrid

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Insituto Valenciano de Infertilida

Madrid, Madrid, Spain

Site Status

Countries

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Spain

Other Identifiers

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MAD-NB-08-2012-01

Identifier Type: -

Identifier Source: org_study_id

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