Global Registry for Endovascular Aortic Treatment (GREAT)

NCT ID: NCT01658787

Last Updated: 2024-10-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

4600 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-12-31

Study Completion Date

2027-06-30

Brief Summary

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Prospective, observational Registry to obtain data on device performance and clinical outcomes.

Detailed Description

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This is a prospective observational cohort Registry designed to obtain data on device performance and clinical outcomes of patients treated with Gore Endovascular Aortic products.

Conditions

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Multiple Pathologies

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Endovascular aortic repair

Patients treated with Gore Endovascular Aortic Products.

Endovascular aortic repair

Intervention Type DEVICE

Treatment with Gore Endovascular Aortic Products.

Interventions

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Endovascular aortic repair

Treatment with Gore Endovascular Aortic Products.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Minimum age required by state regulations
* Indication for aortic endovascular stent graft repair
* Signed informed consent

Exclusion Criteria

* N/A
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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W.L.Gore & Associates

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ross Milner, MD, FACS

Role: PRINCIPAL_INVESTIGATOR

The University of Chicago Medicine & Biological Sciences

Dennis Gable, MD

Role: PRINCIPAL_INVESTIGATOR

Baylor Research Institute

Pierre Galvagni Silveira, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Coris Medicina Avançada

Steven R Dubenec, MD

Role: PRINCIPAL_INVESTIGATOR

Royal Prince Alfred Hospital, Sydney, Australia

Santi Trimarchi, MD

Role: PRINCIPAL_INVESTIGATOR

IRCCS Policlinico S. Donato

Locations

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The University of Chicago Medicine & Biological Sciences

Chicago, Illinois, United States

Site Status

Baylor Research Institute

Plano, Texas, United States

Site Status

Royal Prince Alfred Hospital

Camperdown, New South Wales, Australia

Site Status

Coris Medicina Avançada

Florianópolis, , Brazil

Site Status

Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico

Milan, , Italy

Site Status

IRCCS Policlinico San Donato

Milan, , Italy

Site Status

Countries

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United States Australia Brazil Italy

References

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Grassi V, Trimarchi S, Weaver F, de Beaufort HWL, Azzizzadeh A, Upchurch GR Jr, Piffaretti G, Lomazzi C; GREAT participants. Endovascular repair of descending thoracic aortic aneurysms-a mid-term report from the Global Registry for Endovascular Aortic Treatment (GREAT). Eur J Cardiothorac Surg. 2022 Jan 24;61(2):357-364. doi: 10.1093/ejcts/ezab366.

Reference Type DERIVED
PMID: 34392333 (View on PubMed)

Baxter RD, Hansen SK, Gable CE, DiMaio JM, Shutze WP, Gable DR; GREAT Investigators. Outcomes of Open Versus Percutaneous Access for Patients Enrolled in the GREAT Registry. Ann Vasc Surg. 2021 Jan;70:370-377. doi: 10.1016/j.avsg.2020.06.033. Epub 2020 Jun 27.

Reference Type DERIVED
PMID: 32603847 (View on PubMed)

Piffaretti G, Grassi V, Lomazzi C, Brinkman WT, Navarro TP, Jenkins MP, Trimarchi S; GREAT participants. Thoracic endovascular stent graft repair for ascending aortic diseases. J Vasc Surg. 2019 Nov;70(5):1384-1389.e1. doi: 10.1016/j.jvs.2019.01.075. Epub 2019 May 21.

Reference Type DERIVED
PMID: 31126763 (View on PubMed)

Shutze W, Suominen V, Jordan W, Cao P, Oweida S, Milner R. The incidence and effect of noncylindrical neck morphology on outcomes after endovascular aortic aneurysm repair in the Global Registry for Endovascular Aortic Treatment. J Vasc Surg. 2018 Dec;68(6):1714-1724. doi: 10.1016/j.jvs.2018.03.394. Epub 2018 May 24.

Reference Type DERIVED
PMID: 29803683 (View on PubMed)

Briggs C, Babrowski T, Skelly C, Milner R. Anatomic and clinical characterization of the narrow distal aorta and implications after endovascular aneurysm repair. J Vasc Surg. 2018 Oct;68(4):1030-1038.e1. doi: 10.1016/j.jvs.2017.12.073. Epub 2018 May 22.

Reference Type DERIVED
PMID: 29802041 (View on PubMed)

Other Identifiers

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GRT 10-11

Identifier Type: -

Identifier Source: org_study_id

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