Renal Retention of Microbubbles

NCT ID: NCT01647464

Last Updated: 2016-04-28

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 10 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2012-07-31
• Study Completion Date: 2012-10-31

Brief Summary

Flank pain has been reported with ultrasound (US) contrast agents. The purpose of this study is to determine whether there is retention of ultrasound contrast agents in the renal microcirculation, which has been described in mice.

Detailed Description

In this study patients undergoing clinically indicated contrast echocardiography will have renal ultrasound performed 10 minutes after completion of contrast infusion to determine the presence and location of renal retention of lipid microbubbles.

Conditions

- Study Focus: Renal Retention of Lipid Microbubbles

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: PROSPECTIVE

Study Groups

Contrast administration

Patients undergoing contrast-enhanced echo.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Undergoing clinically indicated contrast echo
• adequate renal ultrasound images

Exclusion Criteria

• chronic inflammatory disease
• known kidney disease
• immunomodulatory therapy

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 90 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Oregon Health and Science University

OTHER

Sponsor Role: lead

Responsible Party

Jonathan R. Lindner, MD

Professor of Medicine

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Oregon Health & Science University

Portland, Oregon, United States

Countries

United States

Other Identifiers

MBretention

Identifier Type: -

Identifier Source: org_study_id