Brain Functional Connectivity Changes Following Cognitive Rehabilitation in Multiple Sclerosis: an fMRI Study

NCT ID: NCT01628276

Last Updated: 2014-09-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-07-31

Study Completion Date

2013-10-31

Brief Summary

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This trial seeks to investigate brain network changes following cognitive rehabilitation in MS patients. The investigators hypothesize that rehabilitation interventions improve connectivity in the brain.Novel Magnetic Resonance Imaging technique is performed to investigate changes in brain plasticity.

Detailed Description

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Conditions

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MS (Multiple Sclerosis)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Rehab first

Group Type EXPERIMENTAL

Cog Rehab

Intervention Type BEHAVIORAL

Cognitive rehab for MS patients

Rehab Second

Group Type EXPERIMENTAL

Cog Rehab

Intervention Type BEHAVIORAL

Cognitive rehab for MS patients

Non Rehab

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Cog Rehab

Cognitive rehab for MS patients

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Definitive MS diagnosis
* Right handedness
* EDSS 0-4
* No relapse in past 6 weeks
* Willing to consent and participate in the study

Exclusion Criteria

* Pregnancy
* Left handedness
* Neurologic or psychiatric disorder other than MS
Minimum Eligible Age

18 Years

Maximum Eligible Age

54 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Sina Hospital, Iran

OTHER

Sponsor Role lead

Responsible Party

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Mohammad Ali Sahraian

Vice President

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Sina Hospital

Tehran, Tehran Province, Iran

Site Status

Countries

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Iran

Other Identifiers

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MSRC-AE-DCM-1

Identifier Type: -

Identifier Source: org_study_id

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