Radial Artery Versus Saphenous Vein Patency (RSVP) Trial - 10 Year Follow-up

NCT ID: NCT01622387

Last Updated: 2019-03-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2011-10-13

Study Completion Date

2014-07-03

Brief Summary

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During coronary bypass surgery, veins are taken from the leg and applied to the heart and aorta to 'bypass' narrowings in the coronary arteries. However using an artery in the chest, the internal mammary artery, means that the bypass lasts longer than using veins. The investigators recently showed that using an artery from the arm as a bypass vessel, the radial artery, also had less furring up than veins 5 years after surgery. Now the investigators would like to ask patients to come back for an angiogram 10 years following surgery.

Detailed Description

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Conditions

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Coronary Artery Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Radial artery

Use of the radial artery as a conduit in CABG surgery

Group Type EXPERIMENTAL

Coronary artery bypass (CABG) surgery using a radial arterial conduit

Intervention Type PROCEDURE

Use of radial artery as a bypass conduit/graft to the left circumflex coronary artery region of the heart in CABG surgery

Long saphenous vein

Use of long saphenous vein as a conduit in CABG surgery

Group Type ACTIVE_COMPARATOR

Coronary artery bypass surgery using a long saphenous vein conduit

Intervention Type PROCEDURE

Use of long saphenous vein as a graft/conduit vessel to the left circumflex coronary artery region of the heart in CABG surgery

Interventions

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Coronary artery bypass (CABG) surgery using a radial arterial conduit

Use of radial artery as a bypass conduit/graft to the left circumflex coronary artery region of the heart in CABG surgery

Intervention Type PROCEDURE

Coronary artery bypass surgery using a long saphenous vein conduit

Use of long saphenous vein as a graft/conduit vessel to the left circumflex coronary artery region of the heart in CABG surgery

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Included in the RSVP study
* Willing to attend for coronary angiography
* Willing to give written informed consent

Exclusion Criteria

* Contraindication to coronary angiography
* participation in research project within previous 60 days
* unwilling to give written informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Imperial College London

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Peter Collins, MA, MD, FRCP

Role: PRINCIPAL_INVESTIGATOR

Imperial College London, and RBHFT

Neil Moat, MD, FRCS

Role: STUDY_DIRECTOR

Royal Brompton & Harefield NHS Foundation Trust

Locations

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Royal Brompton & Harefield NHS Foundation Trust

London, , United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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P38558

Identifier Type: -

Identifier Source: org_study_id

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