Assessment of Hemodynamic Response in Cardiopulmonary Bypass Graft After Cardiopulmonary Bypass Using Transesophegeal Echocardiography
NCT ID: NCT01616069
Last Updated: 2015-06-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
81 participants
INTERVENTIONAL
2012-02-29
2013-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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epinephrine
Assessment of systolic and diastolic heart function during CABAG with CPB with levosimendan using TEE.
epinephrine and levosimendan
epinephrine (0,06mcg/kg/min), levosimendan (0,2 mcg/kg/min)
levosimendan
Assessment of systolic and diastolic heart function during CABAG with CPB with epinephrine using TEE.
epinephrine and levosimendan
epinephrine (0,06mcg/kg/min), levosimendan (0,2 mcg/kg/min)
Interventions
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epinephrine and levosimendan
epinephrine (0,06mcg/kg/min), levosimendan (0,2 mcg/kg/min)
Eligibility Criteria
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Inclusion Criteria
* EF \> 35%
* Elective CABG surgery
Exclusion Criteria
* Severe valvular regurgitation or stenoses
* Chest pain
* Cardiogenic shock
45 Years
65 Years
ALL
No
Sponsors
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Universidade Federal do Rio de Janeiro
OTHER
National Institute of Cardiology/Ministry of Health
UNKNOWN
Federal University of Juiz de Fora
OTHER
Responsible Party
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Marcello F Salgado Filho, MD
Principal investigator
Principal Investigators
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Marcello F Salgado Filho, Master
Role: PRINCIPAL_INVESTIGATOR
National Institute of Cardiology/Ministry of Health
Locations
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National Institute of Cardiology / Ministry of Health
Rio de Janeiro, Rio de Janeiro, Brazil
Countries
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References
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Chung PC, Huang PC, Liu YF, Chen KB. Transesophageal echocardiography, more than a diagnostic tool: use during surgical ligation of coronary artery fistulae - a case report. J Cardiothorac Surg. 2012 Apr 6;7:28. doi: 10.1186/1749-8090-7-28.
De Mey N, Couture P, Laflamme M, Denault AY, Perrault LP, Deschamps A, Rochon AG. Intraoperative changes in regional wall motion: can postoperative coronary artery bypass graft failure be predicted? J Cardiothorac Vasc Anesth. 2012 Jun;26(3):371-5. doi: 10.1053/j.jvca.2012.02.005. Epub 2012 Mar 28.
Salgado Filho MF, Siciliano A, Siciliano A, Oliveira AJ, Salgado J, Palitot I. The importance of transesophageal echocardiography in heart harvesting for cardiac transplantation. Rev Bras Anestesiol. 2012 Mar-Apr;62(2):262-8. doi: 10.1016/S0034-7094(12)70124-1.
Fattouch K, Castrovinci S, Murana G, Novo G, Caccamo G, Bertolino EC, Sampognaro R, Novo S, Ruvolo G, Lancellotti P. Multiplane two-dimensional versus real time three-dimensional transesophageal echocardiography in ischemic mitral regurgitation. Echocardiography. 2011 Nov;28(10):1125-32. doi: 10.1111/j.1540-8175.2011.01528.x. Epub 2011 Oct 17.
Salgado Filho MF, Barral M, Barrucand L, Cavalcanti IL, Vercosa N. A Randomized Blinded Study of the Left Ventricular Myocardial Performance Index Comparing Epinephrine to Levosimendan following Cardiopulmonary Bypass. PLoS One. 2015 Dec 14;10(12):e0143315. doi: 10.1371/journal.pone.0143315. eCollection 2015.
Related Links
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Related Info
Related Info
Other Identifiers
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0362/14-12-2011
Identifier Type: -
Identifier Source: org_study_id
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