Comparison of Sublingual Misoprostol and Intravenous Oxytocin in Active Management of the Third Stage of Labor

NCT ID: NCT01612390

Last Updated: 2012-06-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

180 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-08-31

Study Completion Date

2013-12-31

Brief Summary

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Sublingual misoprostol is superior to oxytocin in reduction of blood loss during the third and fourth stages of labor

Detailed Description

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Sublingual misoprostol is superior to oxytocin in reduction of blood loss during the third and fourth stages of labor as The data from a pharmacokinetics study suggested that the bioavaiblitiy of misoprostol after sub-lingual administration was higher than those after oral or vaginal administration

Conditions

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Postpartum Hemorrhage Prevention by Using Oxytocin Verses Misoprostol

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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group 1

receive 400 Mg sublingual misoprostol.

No interventions assigned to this group

group 2

receive 600 Mg sublingual misoprostol.

No interventions assigned to this group

group 3

receive 5IU of intravenous oxytocin.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Women with aheathy singleton pregnancy in spontaneous or induced labor at term .

Exclusion Criteria

* Hypersensitivity/Contraindication to prostaglandins Antepartum hemorrhage Multiple pregnancy Cardiac disease Malpresentation Rhesus- negative mother hypersensitive disorders Severe anaemia(hemoglobin\<7g/dl)
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Ain Shams University

OTHER

Sponsor Role collaborator

Rasha Mohammed Mohammed Badawi

OTHER

Sponsor Role lead

Responsible Party

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Rasha Mohammed Mohammed Badawi

RBadawi

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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RBadawi mohamed, M.B;B.CH

Role: PRINCIPAL_INVESTIGATOR

Ain Shams University

Locations

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AinShamsU

Cairo, , Egypt

Site Status

Countries

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Egypt

Central Contacts

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Rasha mohamed, M.B;B.CH

Role: CONTACT

Other Identifiers

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hit 1234

Identifier Type: -

Identifier Source: org_study_id

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