CDC Prevention Epicenters Wake Up and Breathe Collaborative
NCT ID: NCT01583413
Last Updated: 2013-10-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
3342 participants
INTERVENTIONAL
2012-05-31
2013-10-31
Brief Summary
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The primary aim of this study is to determine the impact of an opt-out protocol for paired daily sedative interruptions and spontaneous breathing trials on VAP rates using a new streamlined VAP definition. The investigators will evaluate the responsiveness of CDC's proposed new surveillance definitions for ventilator-associated events to this quality improvement initiative. The study will be nested within the Epicenters Streamlined versus Conventional VAP Surveillance Study. Nine of the 18 hospitals in the larger study will be participating in this intervention arm.
Detailed Description
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Conditions
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Keywords
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Opt Out Protocol
Daily SAT & SBT
Nurse and/or respiratory therapist led daily awakenings from sedation (spontaneous awakening trial, or SAT) and daily performance of a spontaneous breathing trial (SBT) among mechanically ventilated, critically ill patients in participating ICUs.
Interventions
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Daily SAT & SBT
Nurse and/or respiratory therapist led daily awakenings from sedation (spontaneous awakening trial, or SAT) and daily performance of a spontaneous breathing trial (SBT) among mechanically ventilated, critically ill patients in participating ICUs.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
ALL
No
Sponsors
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Centers for Disease Control and Prevention
FED
Washington University School of Medicine
OTHER
Rush University Medical Center
OTHER
University of Pennsylvania
OTHER
Duke University
OTHER
North Shore Medical Center
OTHER
Harvard Pilgrim Health Care
OTHER
Responsible Party
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Michael Klompas MD, MPH, FRCPC
Principal Investigator
Principal Investigators
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Michael Klompas, MD, MPH
Role: PRINCIPAL_INVESTIGATOR
Harvard Pilgrim Health Care
Locations
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Chicago Prevention Epicenter
Chicago, Illinois, United States
North Shore Medical Center
Salem, Massachusetts, United States
Washington University Prevention Epicenter
St Louis, Missouri, United States
Duke University Prevention Epicenter
Durham, North Carolina, United States
University of Pennsylvania Prevention Epicenter
Philadelphia, Pennsylvania, United States
Countries
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References
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Klompas M, Anderson D, Trick W, Babcock H, Kerlin MP, Li L, Sinkowitz-Cochran R, Ely EW, Jernigan J, Magill S, Lyles R, O'Neil C, Kitch BT, Arrington E, Balas MC, Kleinman K, Bruce C, Lankiewicz J, Murphy MV, E Cox C, Lautenbach E, Sexton D, Fraser V, Weinstein RA, Platt R; CDC Prevention Epicenters. The preventability of ventilator-associated events. The CDC Prevention Epicenters Wake Up and Breathe Collaborative. Am J Respir Crit Care Med. 2015 Feb 1;191(3):292-301. doi: 10.1164/rccm.201407-1394OC.
Other Identifiers
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PH000410A-2
Identifier Type: -
Identifier Source: org_study_id