Insecticidal School Uniforms for Dengue Prevention in Thailand

NCT ID: NCT01563640

Last Updated: 2015-09-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

1825 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-03-31

Study Completion Date

2014-12-31

Brief Summary

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This is a randomised controlled trial that will be conducted in eastern Thailand in a group of schools with approximately 2,000 students aged 7-15 years. Pre-fabricated school uniforms will be commercially treated to ensure consistent high quality of insecticide impregnation with permethrin. A double-blind randomised cross-over trial at the school level will cover two dengue transmission seasons.

Detailed Description

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Conditions

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Dengue

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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normal school uniforms

washing only

Group Type PLACEBO_COMPARATOR

washing

Intervention Type OTHER

normal washing of school uniforms, without permethrin insecticide impregnation

insecticide-treated school uniforms

washing and insecticide treatment

Group Type EXPERIMENTAL

permethrin insecticide

Intervention Type OTHER

commercial permethrin insecticide impregnation of clothing before transmission season

Interventions

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permethrin insecticide

commercial permethrin insecticide impregnation of clothing before transmission season

Intervention Type OTHER

washing

normal washing of school uniforms, without permethrin insecticide impregnation

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* pupils in participating schools

Exclusion Criteria

* skin sensitivity, exema
Minimum Eligible Age

7 Years

Maximum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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European Union

OTHER

Sponsor Role collaborator

Umeå University

OTHER

Sponsor Role lead

Responsible Party

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Peter Byass

Professor of Global Health

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Annelies Wilder-Smith, MD

Role: PRINCIPAL_INVESTIGATOR

Umeå University

Locations

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Centre of Excellence for Vectors and Vector-Borne Diseases, Mahidol University

Salaya, , Thailand

Site Status

Countries

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Thailand

References

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Kittayapong P, Olanratmanee P, Maskhao P, Byass P, Logan J, Tozan Y, Louis V, Gubler DJ, Wilder-Smith A. Mitigating Diseases Transmitted by Aedes Mosquitoes: A Cluster-Randomised Trial of Permethrin-Impregnated School Uniforms. PLoS Negl Trop Dis. 2017 Jan 19;11(1):e0005197. doi: 10.1371/journal.pntd.0005197. eCollection 2017 Jan.

Reference Type DERIVED
PMID: 28103255 (View on PubMed)

Wilder-Smith A, Byass P, Olanratmanee P, Maskhao P, Sringernyuang L, Logan JG, Lindsay SW, Banks S, Gubler D, Louis VR, Tozan Y, Kittayapong P. The impact of insecticide-treated school uniforms on dengue infections in school-aged children: study protocol for a randomised controlled trial in Thailand. Trials. 2012 Nov 15;13:212. doi: 10.1186/1745-6215-13-212.

Reference Type DERIVED
PMID: 23153360 (View on PubMed)

Related Links

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Other Identifiers

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282589-T

Identifier Type: -

Identifier Source: org_study_id

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