Anesthesia During Neurophysiologic Monitoring in Scoliosis Patients

NCT ID: NCT01549873

Last Updated: 2015-02-26

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-01-31

Study Completion Date

2013-06-30

Brief Summary

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When patients have spinal surgery, electrodes are placed on the body to measure motor evoked potentials (MEP) and somatosensory evoked potentials (SSEP). Many hospitals only use IV anesthesia because they feel that measuring MEP and SSEP is easier using IV anesthesia. At this hospital the investigators typically use inhaled anesthesia and are able to successfully measure MEP and SSEP. This is a study to find out if one method of anesthesia is better than the other for measuring MEP and SSEP.

Detailed Description

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Conditions

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Idiopathic Scoliosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Total intravenous anesthesia (TIVA)

Group Type ACTIVE_COMPARATOR

propofol

Intervention Type DRUG

Propofol adjusted to maintain the bispectral index at 40-60.

Inhaled anesthesia

Group Type ACTIVE_COMPARATOR

Desflurane

Intervention Type DRUG

Desflurane adjusted to maintain the bispectral index at 40-60.

Interventions

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propofol

Propofol adjusted to maintain the bispectral index at 40-60.

Intervention Type DRUG

Desflurane

Desflurane adjusted to maintain the bispectral index at 40-60.

Intervention Type DRUG

Other Intervention Names

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Diprivan Suprane

Eligibility Criteria

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Inclusion Criteria

* Patients with idiopathic scoliosis.

Exclusion Criteria

* Patients with neuromuscular scoliosis.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Nationwide Children's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Joseph D. Tobias

Chairman, Dept. of Anesthesiology & Pain Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Joseph D Tobias, MD

Role: PRINCIPAL_INVESTIGATOR

Nationwide Children's Hospital

Locations

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Nationwide Children's Hospital

Columbus, Ohio, United States

Site Status

Countries

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United States

Other Identifiers

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IRB11-00727

Identifier Type: -

Identifier Source: org_study_id

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